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Role of P-Selectin in the Development of Hemostasis Disorders in COVID-19
This is a review of data on the impact of COVID-19 on blood clotting. An important feature of the pathogenesis of severe acute respiratory syndrome...
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The neutrophil-to-apolipoprotein A1 ratio is associated with adverse outcomes in patients with acute decompensated heart failure at different glucose metabolic states: a retrospective cohort study
BackgroundThe present study was performed to assess the association between the neutrophil-to-apolipoprotein A1 ratio (NAR) and outcomes in patients...
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Thromboresistance of Polyurethane Plates Modified with Quaternized Chitosan and Heparin
AbstractTo obtain modified polyurethane (PU) plates, quaternized chitosan (QuatCh; degree of substitution 50%, degree of deacetylation 87%) and...
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Ascidian (Chordata-Tunicata) Glycosaminoglycans: Extraction, Purification, Biochemical, and Spectroscopic Analysis
Sulfate polysaccharides with unique structures of the chondroitin/dermatan and heparin/heparan families of sulfated glycosaminoglycans have been... -
Horizons of Heparin Therapy in COVID-19 and Pandemic-Related Diseases
AbstractThe disease caused by the coronavirus SARS-CoV-2, named COVID-19, has been spread around the world at a high transmission rate. It was...
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What Can Comparisons of Randomised and Non-Randomised Studies Tell Us?
A strand of research in Evidence-Based Medicine (EBM) compares results of randomised and non-randomised studies to empirically assess the... -
Recent Advances in Insect Biotechnology
Insect biotechnology is the use of insects and their derivatives for agriculture, industrial and human welfare. Biotechnological tools apply to... -
Prospects for the Use of Marine Sulfated Fucose-Rich Polysaccharides in Treatment and Prevention of COVID-19 and Post-COVID-19 Syndrome
AbstractSymptoms of the new coronavirus infection that appeared in 2019 (COVID-19) range from low fever and fatigue to acute pneumonia and multiple...
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Fungal Therapeutic Enzymes: Utility in the Treatment of Human Ailments
This chapter provides an overview of fungal therapeutic enzymes and advancements in applications of these biopharmaceuticals for the treatment of a... -
Glycosaminoglycan Quality Control by Monosaccharide Analysis
Glycosaminoglycans (GAGs) are heterogeneous biomacromolecules made by all animal cells with overlap** molecular weight and high negative charge... -
Physiological and transcriptomic effects of formulated diets including the prebiotics inulin, β-glucan, and chitosan on juveniles of Totoaba macdonaldi
In this study, we evaluated the effects of three prebiotics (inulin, β-glucan, and chitosan) on the physiological performance of Totoaba macdonaldi ...
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Assessment of rodenticide resistance, eradication units, and pathogen prevalence in black rat populations from a Mediterranean biodiversity hotspot (Pontine Archipelago)
Biological invasions are a growing threat to biodiversity. The black rat, one of the worst pest in the world, is responsible for extensive population...
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α1-Adrenergic Stimulation Increases Platelet Adhesion to Endothelial Cells Mediated by TRPC6
Stimulation of a1-adrenergicAdrenergic nervous systemNervous system is increased during systemic inflammationInflammation and other pathological... -
Influence of 21-Day Head-Down Bed Rest on the Hemostasis System of a Healthy Human
AbstractThe bed rest experiment involved six healthy men aged 24 to 41 years. The subjects were in the supine position for 21 days, the angle of...
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Use of Rabbit Models to Study Atherosclerosis
Rabbits are a useful animal model for examining human hyperlipidemia and atherosclerosis because they have unique features of lipoprotein metabolism... -
Isolation of Circulating Extracellular Vesicles by High-Performance Size-Exclusion Chromatography
Circulating extracellular vesicles (EVs) are gaining increased attention as carriers of proteins, nucleic acids, and lipids. Blood contains EVs from... -
Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a severe disease that emerged during the COVID-19 pandemic. Although recognized as an...
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Plasma and serum metabolic analysis of healthy adults shows characteristic profiles by subjects’ sex and age
IntroductionPre-analytical factors like sex, age, and blood processing methods introduce variability and bias, compromising data integrity, and thus...
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The Role of Vitamin K in the Development of Neurodegenerative Diseases
AbstractNeurodegenerative diseases are a growing global health problem with enormous consequences for individuals and society. The most common...