Search
Search Results
-
Identification of high-risk non-synonymous SNPs (nsSNPs) in DNAH1 and DNAH17 genes associated with male infertility: a bioinformatics analysis
Male infertility is a significant reproductive issue affecting a considerable number of couples worldwide. While there are various causes of male...
-
Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection
Eighteen of the 20 amino acids are each encoded by more than one synonymous codon. Due to differential transfer RNA supply within the cell,...
-
Allelic Polymorphism of Anthrax Pathogenicity Factor Genes as a Means of Estimating Microbiological Risks Associated with Climate Change
AbstractClimate change brings new risks of emergence of especially dangerous diseases. The paper reports the possibility of assessing the pathogenic...
-
Rates of evolutionary change of resident Escherichia coli O157:H7 differ within the same ecological niche
BackgroundShiga toxin-producing Escherichia coli (STEC) O157:H7 is a pathogen known to reside in cattle feedlots. This retrospective study examined...
-
Lilac (Syringa oblata) genome provides insights into its evolution and molecular mechanism of petal color change
Color change during flower opening is common; however, little is understood on the biochemical and molecular basis related. Lilac ( Syringa oblata ), a...
-
Mangroves of Malaysia: a comprehensive review on ecosystem functions, services, restorations, and potential threats of climate change
Mangroves stand as unique blue-carbon ecosystems in intertidal tropical and subtropical coastal regions, renowned for their significant contributions...
-
Unveiling polymorphism and protein structure prediction insights in diacylglycerol O-acyltransferase 1 and telethonin genes of Egyptian buffalo
BackgroundThe Egyptian buffalo has a sizable impact on Egypt's agricultural sector and food supply. It is regarded as the main dairy animal and an...
-
Bioprospecting for plant resilience to climate change: mycorrhizal symbionts of European and American beachgrass (Ammophila arenaria and Ammophila breviligulata) from maritime sand dunes
Climate change and global warming have contributed to increase terrestrial drought, causing negative impacts on agricultural production. Drought...
-
The evolutionary genomics of species’ responses to climate change
Climate change is a threat to biodiversity. One way that this threat manifests is through pronounced shifts in the geographical range of species over...
-
Synonymous Codon Usage—a Guide for Co-Translational Protein Folding in the Cell
Abstract —In the cell, protein folding begins during protein synthesis/translation and thus is a co-translational process. Co-translational protein...
-
Land use and life history constrain adaptive genetic variation and reduce the capacity for climate change adaptation in turtles
BackgroundRapid anthropogenic climate change will require species to adapt to shifting environmental conditions, with successful adaptation dependent...
-
Parsing the synonymous mutations in the maize genome: isoaccepting mutations are more advantageous in regions with codon co-occurrence bias
BackgroundSynonymous mutations do not change amino acids but do sometimes change the tRNAs (anticodons) that decode a particular codon. An...
-
Resilience Management at the Landscape Level: Fostering Mitigation and Adaptations to Global Change Based on Forest Socio-ecosystems
Agroforestry landscapes provide a variety of ecosystem goods and services at both the farm and landscape levels. They also host thousands of rural...
-
Detecting macroevolutionary genotype–phenotype associations using error-corrected rates of protein convergence
On macroevolutionary timescales, extensive mutations and phylogenetic uncertainty mask the signals of genotype–phenotype associations underlying...
-
Comparative analysis of codon usage bias in chloroplast genomes of ten medicinal species of Rutaceae
Rutaceae family comprises economically important plants due to their extensive applications in spices, food, oil, medicine, etc. The Rutaceae plants...
-
The efficacy and safety of SARS-CoV-2 vaccines mRNA1273 and BNT162b2 might be complicated by rampant C-to-U RNA editing
The SARS-CoV-2 RNA vaccines are smartly designed to increase the synonymous codon usage by introducing multiple U-to-C mutations. This design would...
-
Single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of prion protein gene (PRNP) in Nigerian livestock species
BackgroundPrion diseases, also known as transmissible spongiform encephalopathies (TSEs) remain one of the deleterious disorders, which have affected...
-
The 29-nucleotide deletion in SARS-CoV: truncated versions of ORF8 are under purifying selection
BackgroundAccessory proteins have diverse roles in coronavirus pathobiology. One of them in SARS-CoV (the causative agent of the severe acute...
-
The relative role of intrinsic and extrinsic drivers in regulating population change and survival of African wild dogs (Lycaon pictus)
Evaluating how intrinsic (intraspecific density), extrinsic (interspecific density and prey density) and anthropogenic (management intervention)...
-
Climate change-related changes in cephalopod biodiversity on the North East Atlantic Shelf
Global studies imply that cephalopods have benefited from climate change. However, in most areas, species-specific long-term cephalopod data sets do...
