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Influence of CYP2C19*2 Polymorphism on Clinical Outcomes in Moldova’s Patients Treated with Clopidogrel After Percutaneous Coronary Intervention
Clopidogrel is one of the most commonly antiplatelet agents used for the secondary prevention of atherothrombotic events in patients with...
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The association of IL-17A rs2275913 single nucleotide polymorphism with anti-tuberculous drug resistance in patients with pulmonary tuberculosis
BackgroundDrug-resistant Tuberculosis (DR-TB) is a global health burden with high morbidity and mortality in develo** countries including Egypt....
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Allelic Polymorphism of CSN3 and Dgat1 Genes in Herds of Black-and-White and Kholmogorsky Cattle
The purpose of the research was to study polymorphism and determine the frequency of occurrence of allelic variants for the gene of kappa-casein and...
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Lacaune Sheep Beta-Lactoglobulin (β-LG) Gene Polymorphism and the Relationship of Its Genotypes to Milk Productivity Indices
Along with classical breeding methods, the use of DNA genoty** and the selection of animals of desirable genotypes is promising for improving milk...
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Association of the single nucleotide polymorphism in CAPN3 gene with growth performance in Merino and Garut (MEGA) backcross sheep
BackgroundSheep is one of the commodities of livestock which has been known widely in Indonesia for supporting the national food security....
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Delineating the role of single-nucleotide polymorphism of CYP19 gene on aromatase activity in South Indian women with polycystic ovary syndrome
BackgroundPolycystic ovary syndrome is a common multifactorial endocrinopathy disorder affecting 5–15% of reproductive women worldwide. The CYP19...
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Runtime Polymorphism for Dynamic Camouflaging
The concept of camouflaging the true state of a system among several dummy states, wherein the system dynamically morphs between the different...
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Estimating the role of single-nucleotide polymorphism (rs1800629)-308 G/A of TNF-alpha gene as genetic marker associated with angina pectoris in a sample of Iraqi patients
BackgroundAngina pectoris (AP) occurs when oxygen and other nutrients are insufficient to meet the metabolic needs of the heart muscle. Stable angina...
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Composition and Polymorphism Support in the OpenAPI Ontology
An OpenAPI [5] description details the actions exposed by a REST API. A service is represented by a JSON document describing requests, responses, and...
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Is there a correlation between -174(G/C) polymorphism of IL-6 gene and the incidence of acute myocardial infarction?
BackgroundCardiovascular disease (CVD) remains the major cause of death worldwide. Most CVD can be prevented by addressing risk factors. Acute...
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Polymorphism and mutational diversity of virulence (vcgCPI/vcgCPE) and resistance determinants (aac(3)-IIa, (aacC2, strA, Sul 1, and 11) among human pathogenic Vibrio species recovered from surface waters in South-Western districts of Uganda
BackgroundVibrio species are among the autochthonous bacterial populations found in surface waters and associated with various life-threatening...
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IL28B rs12979860 polymorphism and zinc supplementation affect treatment outcome and liver fibrosis after direct-acting antiviral hepatitis C therapy
BackgroundImpact of interleukin 28B (IL28B) rs12979860 polymorphism on response to direct-acting antivirals agents in HCV genotype 4-infected...
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Contribution of glutathione peroxidase 1 (Pro200Leu) single nucleotide polymorphism and serum homocysteine levels in the risk of acute myocardial infarction in Egyptians
BackgroundOxidative stress is among the most common risk factors in the pathogenesis of acute myocardial infarction (AMI). Glutathione peroxidase 1...
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ApoB gene polymorphism (rs676210) and its pharmacogenetics impact on atorvastatin response among Iraqi population with coronary artery disease
BackgroundDrug response is below genetic influence, proven by the genetic variants. Pharmacogenetics trials are performed in many diseases, including...
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Detection of a novel single nucleotide polymorphism in IGF2 gene with a negative impact on egg production and body weight in Japanese quail (Coturnix japonica)
BackgroundInsulin-like growth factor 2 ( IGF2 ) is one of three hormones that share high structural similarity to insulin. It is involved in several...
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Genetic Polymorphism β-Lactoglobulin Gene in Dubska Pramenka Sheep Breed
Polymorphism exists in β-lactoglobulin (LGB) milk encoding gene in dairy animals, resulting in presence of different protein isoforms in milk. There...
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Design and characterization of a SYBR Green I-based melting curve method for investigation of HER2I655V polymorphism in breast cancer
BackgroundBreast cancer is a disease in which cell grows rapidly forming a mass in the breast. HER2 polymorphisms Ile655Val have been studied as...
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Suitability of target region amplified polymorphism (TRAP) markers to discern genetic variability in sweet sorghum
BackgroundSweet sorghum is an emerging biofuel candidate crop with multiple benefits as a source of biomass energy. Increase of biomass and sugar...
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Lack of Association of CYP2C9:c.430C>T and SCN1A:c.3184A>G Polymorphisms with Epilepsy Risk or Drug Resistance in Childhood Epilepsy Syndromes in Lagos State, Nigeria
Pharmacoresistance has been a constant challenge in managing children with childhood epilepsy syndromes, and this has been attributable in part to...
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Real-time Monitoring of Hydration Reaction of Theophylline Anhydrous via Terahertz Attenuated Total Reflection Time Domain Spectroscopy
In pharmaceuticals, pseudo-polymorphism, e.g., the existence of hydrate and anhydrous forms, affects their physicochemical characteristics....
