Search
Search Results
-
Glowstick-inspired smartphone-readable reporters for sensitive, multiplexed lateral flow immunoassays
The COVID-19 pandemic has increased demand for point-of-care (POC) screening tests such as lateral flow assays (LFAs) and highlighted the need for...
-
Lateral flow test engineering and lessons learned from COVID-19
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical and public health purposes has been demonstrated...
-
Eliminating viscosity bias in lateral flow tests
Despite the widespread application of point-of-care lateral flow tests, the viscosity dependence of these assay results remains a significant...
-
Engineered nanoparticles for clinical assays
Nanoparticles exhibit distinctive physical and chemical properties that make them effective mediators for optical, magnetic or electric signal...
-
Gold-based nanoplatform for a rapid lateral flow immunochromatographic test assay for gluten detection
BackgroundGluten, a food allergen, is available in foods derived from wheat, rye and barley. It damages the small intestine and causes celiac...
-
A Comparison of Single-Sized and Mixed-Sized Particles on Lateral Flow Assay Performance for SARS-CoV-2 Nucleocapsid Protein Detection
There are several factors that can affect the sensitivity and reproducibility of the lateral flow assay, such as the size of gold nanoparticles...
-
Challenges and perspectives in the development of paper-based lateral flow assays
Lateral flow assays (LFAs) have been introduced and developed over the last half century. This technology is widely used as a tool for diagnosis in...
-
-
Paper-Based Biosensors with Lateral/Vertical Flow Assay
The lateral flow assay (LFA), which is a simple paper-based device for the detection and analysis of disease, is now the most predominant diagnostic...
-
A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation
IntroductionLymphatic vessels (LVs) maintain fluid homeostasis by draining excess interstitial fluid, which is accomplished by two distinct LVs:...
-
Development and optimization of thermal contrast amplification lateral flow immunoassays for ultrasensitive HIV p24 protein detection
Detection of human immunodeficiency virus (HIV) p24 protein at a single pg/ml concentration in point-of-care (POC) settings is important because it...
-
The Incubation Time Effects on the Precision and Accuracy of the Glycated Hemoglobin
Health can be easily monitored by performing routine blood assays. The blood science offers complete information about the clinical state of the body...
-
A needle tip CCEA microfluidic device based on enhanced Dean flow for cell washing
Particle/cell washing is an essential technique in biological and clinical manipulations. Herein, we propose a novel circular contraction–expansion...
-
Paper-based multiplex biosensors for inexpensive healthcare diagnostics: a comprehensive review
Multiplex detection is a smart and an emerging approach in point-of-care testing as it reduces analysis time and testing cost by detecting multiple...
-
Drag coefficient on particle agglomerates: a CFD study with experimental validation
The formation of irregularly shaped particle agglomerates is a recurring phenomenon observed in equipment with particle-laden flows, which directly...
-
DropLab: an automated magnetic digital microfluidic platform for sample-to-answer point-of-care testing—development and application to quantitative immunodiagnostics
In point-of-care testing (POCT), tests are performed near patients and results are given rapidly for timely clinical decisions. Immunodiagnostic...
-
Lab-On-A-Chip Technology in Health Care
In the current era when early disease diagnosis is a need of the hour for the proper cure, LOC devices are the most reliable and promising solution....
-
An Overview on SARS-CoV-2 (COVID-19) and Other Human Coronaviruses and Their Detection Capability via Amplification Assay, Chemical Sensing, Biosensing, Immunosensing, and Clinical Assays
A novel coronavirus of zoonotic origin (SARS-CoV-2) has recently been recognized in patients with acute respiratory disease. COVID-19 causative agent...
-
Spike- and nucleocapsid-based gold colloid assay toward the development of an adhesive bandage for rapid SARS-CoV-2 immune response detection and screening
Immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies are important biomarkers used for the diagnosis and screening of severe acute...
-
Emerging Technologies in Diagnostic Virology and Antiviral Strategies
Timely and accurate diagnosis of viral infections has an important role in public healthcare management. Accordingly, there is a growing need to...