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Whole Cell Yeast-Based Biosensors
Analyte detection is a major component of fieldwork, environmental surveillance, and health protection, but lack of resources or access to...
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NIR Light-Promoted Whole-Cell Catalysis Based on a Light-Harvesting Blackbody Bioreactor
Whole-cell catalysis, which utilizes enzymes expressed in whole organism (e.g. bacteria and fungi) as the catalyst, is a specific mode of...
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Nutrient Detection with Whole-Cell Biosensors
Whole-cell biosensor systems (WCB) have become one of the most fascinating analytical systems in recent times due to their low cost, high...
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Highly efficient bioconversion of icariin to icaritin by whole-cell catalysis
BackgroundIcaritin is an aglycone of flavonoid glycosides from Herba Epimedii . It has good performance in the treatment of hepatocellular carcinoma...
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Whole-Cell-Based Fiber-Optic Biosensors
In the last decade, various whole-cell-based fiber-optic biosensors have been described. All of those reports have shown great potential for their...
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Photosynthetic bacteria-based whole-cell inorganic-biohybrid system for multimodal enhanced tumor radiotherapy
The whole-cell inorganic-biohybrid systems show special functions and wide potential in biomedical application owing to the exceptional interactions...
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Whole-cell bioconversion using non-Leloir transglycosylation reactions: a review
Microbial biocatalysts are evolving technological tools for glycosylation research in food, feed and pharmaceuticals. Advances in bioengineered...
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Combining an artificial metathase with a fatty acid decarboxylase in a whole cell for cycloalkene synthesis
Artificial metalloenzymes (ArMs) offer powerful tools to catalyse new-to-nature reactions. Accordingly, ArMs offer great potential to complement...
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Fundamental Building Blocks of Whole-Cell Biosensor Design
Whole-cell biosensors are one of the most popular applications of synthetic biology. Biological sensing mechanisms originating from natural systems...
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Designing a highly efficient type III polyketide whole-cell catalyst with minimized byproduct formation
BackgroundPolyketide synthases (PKSs) are classified into three types based on their enzyme structures. Among them, type III PKSs, catalyzing the...
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High-efficiency depolymerization/degradation of polyethylene terephthalate plastic by a whole-cell biocatalyst
Polyethylene terephthalate (PET) is the most abundantly produced plastic due to its excellent performance, but is also the primary source of poorly...
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Whole-cell one-pot biosynthesis of dodecanedioic acid from renewable linoleic acid
BackgroundDodecanedioic acid (DDA), a typical medium-chain dicarboxylic fatty acid with widespread applications, has a great synthetic value and a...
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Modular bioengineering of whole-cell catalysis for sialo-oligosaccharide production: coordinated co-expression of CMP-sialic acid synthetase and sialyltransferase
BackgroundIn whole-cell bio-catalysis, the biosystems engineering paradigm shifts from the global reconfiguration of cellular metabolism as in...
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Whole-cell catalyze L-dopa to dopamine via co-expression of transport protein AroP in Escherichia coli
Dopamine is high-value compound of pharmaceutical interest, but its industrial scale production mostly focuses on chemical synthesis, possessing...
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Application of Bacterial Whole-Cell Biosensors in Health
Biosensors employ biological systems to detect an analyte and report it by transducing a detectable signal. Application of synthetic biology design...
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Nitrification activity in the presence of 2-chlorophenol using whole nitrifying cells and cell-free extracts: batch and SBR assays
Kinetic assays with a nitrifying consortium with whole nitrifying cells amended with 5 mg 2-CP-C/L and 100, 200, 300, or 500 mg NH 4 + –N/L were carried...
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Efficient acetoin production from pyruvate by engineered Halomonas bluephagenesis whole-cell biocatalysis
Acetoin is an important platform chemical, which has a wide range of applications in many industries. Halomonas bluephagenesis , a chassis for next...
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pH-dependent and whole-cell catalytic decolorization of dyes using recombinant dye-decolorizing peroxidase from Rhodococcus jostii
Dyes in wastewater have adverse effects on the environment and human health. Dye-decolorizing peroxidase (DyP) is a promising biocatalyst to dyes...
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Development of a yeast whole-cell biocatalyst for MHET conversion into terephthalic acid and ethylene glycol
BackgroundOver the 70 years since the introduction of plastic into everyday items, plastic waste has become an increasing problem. With over 360...
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Bioengineering Comamonas testosteroni CNB-1: a robust whole-cell biocatalyst for efficient PET microplastic degradation
The escalating crisis of polyethylene terephthalate (PET) microplastic contamination in biological wastewater treatment systems is a pressing...
