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Concentration and composition of the protein corona as a function of incubation time and serum concentration: an automated approach to the protein corona
Nanoparticles in contact with proteins form a “corona” of proteins adsorbed on the nanoparticle surface. Subsequent biological responses are then...
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The influence of protein corona on Graphene Oxide: implications for biomedical theranostics
Graphene-based nanomaterials have attracted significant attention in the field of nanomedicine due to their unique atomic arrangement which allows...
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Surface antibody changes protein corona both in human and mouse serum but not final opsonization and elimination of targeted polymeric nanoparticles
BackgroundNanoparticles represent one of the most important innovations in the medical field. Among nanocarriers, polymeric nanoparticles (PNPs)...
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Novel brain-targeted nanomicelles for anti-glioma therapy mediated by the ApoE-enriched protein corona in vivo
BackgroundThe interactions between nanoparticles (NPs) and plasma proteins form a protein corona around NPs after entering the biological...
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Multifunctional exosome-mimetics for targeted anti-glioblastoma therapy by manipulating protein corona
Targeted drug delivery to the glioblastoma (GBM) overcoming blood–brain barrier (BBB) has been challenging. Exosomes are promising vehicles for brain...
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Poly (N-vinylpyrrolidone) modification mitigates plasma protein corona formation on phosphomolybdate-based nanoparticles
Phosphomolybdate-based nanoparticles (PMo 12 -based NPs) have been commonly applied in nanomedicine. However, upon contact with biofluids, proteins are...
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Identifying cell receptors for the nanoparticle protein corona using genome screens
Nanotechnology provides platforms to deliver medical agents to specific cells. However, the nanoparticle’s surface becomes covered with serum...
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Unveiling the Bio-corona Fingerprinting of Potential Anticancer Carbon Nanotubes Coupled with d-Amino Acid Oxidase
The oxidation therapy, based on the controlled production of Reactive Oxygen Species directly into the tumor site, was introduced as alternative...
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Unusual zymogen activation patterns in the protein corona of Ca-zeolites
Zymogen (prothrombin) activation is central to the process of haemostasis (blood clotting) in the body, preventing serious blood loss and death from...
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Large-Scale Production and Business Plan for Novel Corona Vaccine
Frontline healthcare workers will play a central role in encouraging COVID-19 vaccination. Many studies have found that physicians are the most...
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Effect of Et2Zn on Binding Spike Protein of SARS-Cov-2 and ACE2 from Cell Membrane
AbstractCorona virus’s connection to the cell is through spike protein to ACE2 from cell membrane. This connection was modeled using Density...
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Automation and low-cost proteomics for characterization of the protein corona: experimental methods for big data
Nanoparticles used in biological settings are exposed to proteins that adsorb on the surface forming a protein corona . These adsorbed proteins...
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Metamaterial-Based Sensors Loaded Corona-Shaped Resonator for COVID-19 Detection by Using Microwave Techniques
The paper proposes microwave-based metamaterial-based sensors for coronavirus infection detection. A sensor has been developed to calculate the...
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Probing the protein corona around charged macromolecules: interpretation of isothermal titration calorimetry by binding models and computer simulations
Isothermal titration calorimetry (ITC) is a widely used tool to experimentally probe the heat signal of the formation of the protein corona around...
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Medicinal Plants Against SARS-CoV/Corona Virus Infections: Ethnopharmacology, Chemistry, and Clinical and Preclinical Studies
Recently, natural compounds have gained significant importance in health care, as they do not exhibit adverse effects compared to synthetic drugs....
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Biochemical and phylogenetic networks-I: hypertrees and corona products
We have obtained graph-theoretically based topological indices for the characterization of certain graph theoretical networks of biochemical...
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The Effect of Topologies and Refilling Short-chain PEG on Protein Adsorption
PEGylation is the gold standard for constructing protein resistance surfaces. Herein, grafting mPEG-SH and SH-PEG-SH with varied molecular weights...
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Computational modelling studies on in silico missenses in COVID-19 proteins and their effects on ligand–protein interactions
The paper presents the incorporation of in silico missenses and studies the effect of missenses to understand its effect on the ligand–protein...
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Physicochemical and Functional Properties Changes in Myofibrillar Protein Extracted from Channel Catfish by a High-Voltage Electrostatic Field
The effects of high-voltage electrostatic field (HVEF) on the physicochemical and functional properties of myofibrillar protein (MP) extracted from...
