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Impact Study of Gene Expression: Osmotic Control, SOS Response, and Heat Shock Responses
Bacteria live in a dynamic environment with constantly changing temperatures, nutrient levels, and the presence of diverse chemicals. To rapidly...
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DNA-based molecular classifiers for the profiling of gene expression signatures
Although gene expression signatures offer tremendous potential in diseases diagnostic and prognostic, but massive gene expression signatures caused...
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Metabolic Flux Analysis Based on 13C-Labeling Experiments and Integration of the Information with Gene and Protein Expression Patterns
The recent progress on metabolic systems engineering was reviewed, in particular focusing on the metabolic flux analysis (MFA) based on the...
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Changes in Fungal Community and Gene Expression of Specific Ligninolytic Enzymes in Response to Wood Decay
Microbial communities, particularly Basidiomycota fungi, play crucial roles in ecosystem functioning, including wood decay and the recycling of...
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Establishing Gene Expression and Knockout Methods in Esteya vermicola CBS115803
Pine wilt disease, which is caused by the nematode Bursaphelenchus xylophilus , is one of the most destructive forest diseases worldwide. Esteya...
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Decoding the ‘Fifth’ Nucleotide: Impact of RNA Pseudouridylation on Gene Expression and Human Disease
Cellular RNAs, both coding and noncoding are adorned by > 100 chemical modifications, which impact various facets of RNA metabolism and gene...
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Gene Nanovector for Genome Therapy
Gene therapy is a potential approach to deal with complicated diseases that are now untreatable. A critical step in the effective gene therapy is the...
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Refactoring the architecture of a polyketide gene cluster enhances docosahexaenoic acid production in Yarrowia lipolytica through improved expression and genetic stability
BackgroundLong-chain polyunsaturated fatty acids (LC-PUFAs), such as docosahexaenoic acid (DHA), are essential for human health and have been widely...
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Optimization, gene cloning, expression, and molecular docking insights for enhanced cellulase enzyme production by Bacillus amyloliquefaciens strain elh1
BackgroundIn this study, we isolated a cellulase-producing bacterium, Bacillus amyloliquefaciens strain elh, from rice peel. We employed two...
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Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
BackgroundCost-effective production of biofuels from lignocellulose requires the fermentation of d -xylose. Many yeast species within and closely...
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RNA-seq reveals multifaceted gene expression response to Fab production in Escherichia coli fed-batch processes with particular focus on ribosome stalling
BackgroundEscherichia coli is a cost-effective expression system for production of antibody fragments like Fabs. Various yield improvement...
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Green Synthesis and Characterization of Selenium Nanoparticles via Staphylococcus warneri Approach: Antimicrobial and on PhzM Pyocyanin Gene Expression in Pseudomonas aeruginosa
Bacteriocins have been attracting a lot of interest as antibacterial agents in recent decades. Bacteriocins have long been used as food...
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Genome-wide analysis and expression profile of TCP gene family under drought and salinity stress condition in cowpea (Vigna unguiculata (L.) Walp.)
TCP transcription factors are known to regulate abiotic stress condition, but their role in V. unguiculata remains unexplored. So, in silico analysis...
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Gene Editing Tools for Engineering Beneficial Microorganism in Biofertilizer
The exponentially growing global population has demand for sustainable agriculture practices to increase food production. To achieve higher...
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Gene expression profiling and protein–protein interaction analysis reveals the dynamic role of MCM7 in Alzheimer's disorder and breast cancer
The interrelation of cancer and Alzheimer's disorder (AD)-associated molecular mechanisms, reported last decade, paved the path for drug discoveries....
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Identification, Isolation, Cloning, and Expression of a New Alkaline Serine Protease Gene from Native Iranian Bacillus sp. RAM 53 for Use in the Industry
Proteases are one of the most important and widely applicable proteolytic enzymes that are used in various industries. The aim of this study was to...
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Factors regulating cellulolytic gene expression in filamentous fungi: an overview
The growing demand for biofuels such as bioethanol has led to the need for identifying alternative feedstock instead of conventional substrates like...
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Weighted gene co-expression network analysis unveils gene networks regulating folate biosynthesis in maize endosperm
Folates are essential elements for human growth and development, and their deficiency can lead to serious disorders. Waxy maize is a rich source of...
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Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis
RNA molecules with the expanded CAG repeat (eCAGr) may undergo sol–gel phase transitions, but the functional impact of RNA gelation is completely...
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Gene Nanovector for Genome Therapy
Gene therapy is a potential approach to deal with complicated diseases that are now untreatable. A critical step in the effective gene therapy is the...