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Antiviral Potential of Curcumins: Ethnopharmacology, Chemistry, and Clinical Studies Focusing on Mechanism of Action and Future Perspectives
Viruses have always been a serious public health concern, and scientists have worked diligently to make new antiviral medicines. Virus infections...
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Antiviral Agents – Benzazine Derivatives
The review outlines the results of studies of the antiviral activity of quinoline, quinoxaline, and quinazoline derivatives published over the past 5...
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Green-synthesized silver nanoparticle coating on paper for antibacterial and antiviral applications
The use of active packaging has attracted considerable attention over recent years to prevent and decrease the risk of bacterial and viral infection....
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Hepatitis C Virus (HCV) and the Role of Phytochemicals in the Antiviral Effects of Different Medicinal Plants Against Infection
Hepatitis C virus (HCV) infection causes acute as well as chronic inflammation in the liver. Its high prevalence with over 23.7 cases per 100,000...
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Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles: comprehensive spectroscopic study
The direct binding of antiviral agents; Daclatasvir and valacyclovir and green synthesized nanoparticles to salmon sperm DNA have been assessed in a...
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Machine Learning Methods in Antiviral Drug Discovery
The rapid spread of viral infections leads to a considerable amount of newly infected people with a high risk of severe complications and death. The...
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Functional Properties of Grapefruit Seed Extract Embedded Blend Membranes of Poly(vinyl alcohol)/Starch: Potential Application for Antiviral Activity in Food Safety to Fight Against COVID-19
The poly(vinyl alcohol) (PVA) and starch-based polymeric films with a ratio of 2:8 were prepared using solution casting followed by a solvent...
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Synthesis, physical properties, and computational biological activity of N-{[(3(4)-halophenyl)amino]carbonothioyl}adamantane-1-carboxamides
Thioureas containing halogen- and dihalogen-substituted phenyl fragments were obtained based on adamantan-1-ylcarbonyl isothiocyanate in up to 76–94%...
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Identification of antiviral peptide inhibitors for receptor binding domain of SARS-CoV-2 omicron and its sub-variants: an in-silico approach
Omicron, a variant of concern (VOC) of SARS-CoV-2, emerged in South Africa in November 2021. Omicron has been continuously acquiring a series of new...
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Identification of natural antimicrobial peptides mimetic to inhibit Ca2+ influx DDX3X activity for blocking dengue viral infectivity
Viruses are microscopic biological entities that can quickly invade and multiply in a living organism. Each year, over 36,000 people die and nearly...
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Methods of Synthesis and Antiviral Activity of New 4-Alkyl-3-Nitro-1,4-Dihydroazolo[5,1-c][1,2,4]Triazin-4-ols
An azo coupling reaction of α-nitro ketones with 5-diazoazoles was used to obtain 4-alkyl-3-nitro-1,4-dihydroazolo[5,1- с ][1,2,4]triazines, which were...
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Polygalic acid inhibits african swine fever virus polymerase activity: findings from machine learning and in vitro testing
African swine fever virus (ASFV), an extremely contagious virus with high mortality rates, causes severe hemorrhagic viral disease in both domestic...
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Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main protease enzyme of SARS-CoV-2
Computational tools in investigating of spectral heterocyclic compounds ranges based on pyrimidine‑2‑thiones, take some importance in identifying...
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In vitro activity of novel 4-iminohydantoin sulfamide derivatives against human cytomegalovirus
Here, we describe machine learning models, predicted ADMET properties, and analysis in vitro activity of selected 4-iminohydantoin sulfamide...
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Heterogeneous photocatalytic degradation of antiviral drug didanosine mediated by rose bengal and TiO2 nanoparticles
There is a great concern among the researcher to remove the problem of the persistent organic pollutants in wastewater. Pharmaceutical agrochemical...
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Photoinduced Hydrophilicity and Antimicrobial Activity by Photocatalysis
Biodegradable plastics that are decomposed by microorganisms are attracting attention as marine pollution caused by microplastics becomes more...
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Modelling the DFT structural and reactivity study of feverfew and evaluation of its potential antiviral activity against COVID-19 using molecular docking and MD simulations
AbstractThe unavailability of a proper drug against SARS-CoV-2 infections and the emergence of various variants created a global crisis. In the...
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Antiviral Compounds from Seaweeds: An Overview
The interest in macroalgae has been growing worldwide in the recent years, due to the new discoveries regarding the numerous health benefits they...
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Synthesis of 2-adamantyl-containing amines as compounds with potential pharmacological activity
The regularities of the reduction of unsaturated nitriles containing the 2-adamantyl fragment with lithium aluminum hydride and nickel—aluminum alloy...
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Targeting the DENV NS2B-NS3 protease with active antiviral phytocompounds: structure-based virtual screening, molecular docking and molecular dynamics simulation studies
Dengue fever has been a global health concern. Mitigation is a challenging problem due to non-availability of workable treatments. The most difficult...
