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Neuroprotective activity of selenium nanoparticles against the effect of amino acid enantiomers in Alzheimer’s disease
Alzheimer’s disease (AD), the most prevalent neurodegenerative disease, is characterized by extracellular accumulation of amyloid-beta protein (Aβ),...
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The transcriptional factor Clr-5 is involved in cellulose degradation through regulation of amino acid metabolism in Neurospora crassa
BackgroundFilamentous fungi are efficient degraders of plant biomass and the primary producers of commercial cellulolytic enzymes. While the...
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L-glutamic monosodium amino acid-assisted approach to mordenite zeolite synthesis with application in the catalytic cracking of n-hexane
Mordenite was synthesized at 170 ºC under stirring (60 rpm) with different contents of L-glutamic acid monosodium salt (MSG) between 4 and 48 h. The...
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Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water
A core feature of covalent organic frameworks (COFs) is crystallinity, but current crystallization processes rely substantially on trial and error,...
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Photochemical single-step synthesis of β-amino acid derivatives from alkenes and (hetero)arenes
β-Amino acids are frequently found as important components in numerous biologically active molecules, drugs and natural products. In particular, they...
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Site-specific bioorthogonal protein labelling by tetrazine ligation using endogenous β-amino acid dienophiles
The tetrazine ligation is an inverse electron-demand Diels–Alder reaction widely used for bioorthogonal modifications due to its versatility, site...
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Process Integration and Design of Amino Acid Purification Processes for Energy Savings: An Industrial Case Study
Energy minimization study is applied to an amino acids downstream process for L-methionine production currently in operation and energy-saving...
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Electrochemical Response of Redox Amino Acid Encoded Fluorescence Protein for Hydroxychloroquine Sensing
The sudden rise in the demand has led to large-scale production of hydroxychloroquine (HCQ) in the global market for various diseases such as...
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Genome mining for macrolactam-encoding gene clusters allowed for the network-guided isolation of β-amino acid-containing cyclic derivatives and heterologous production of ciromicin A
β-Amino acid-containing macrolactams represent a structurally diverse group of bioactive natural products derived from polyketides; however we are...
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Enhanced production of γ-amino acid 3-amino-4-hydroxybenzoic acid by recombinant Corynebacterium glutamicum under oxygen limitation
BackgroundBio-based aromatic compounds are of great interest to the industry, as commercial production of aromatic compounds depends exclusively on...
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Evaluating Biocompatible Amino Acid-Based Poly(ionic liquid)s for CO2 Absorption
Amino acid-based ionic liquids are biocompatible agents which showed a potential for CO 2 adsorption. On the other hand poly(ionic liquid)s were...
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Kinetics of Thermoinactivation of D-Amino Acid Oxidase OPADAAO1 from the Ogataea parapolymorpha DL-1 Yeast
AbstractOur earlier annotation of the genome of the yeast Ogataea parapolymorpha DL-1 made it possible to identify five genes of potential D-amino...
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The D-amino acid oxidase-carbon nanotubes: evaluation of cytotoxicity and biocompatibility of a potential anticancer nanosystem
The ‘enzyme prodrug therapy’ represents a promising strategy to overcome limitations of current cancer treatments by the systemic administration of...
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Prospects of Application of D-amino Acid Transaminase from Aminobacterium colombiense for (R)-selective Amination of α‑Keto Acids
AbstractD-amino acid transaminase from Aminobacterium colombiense was applied for ( R )-selective amination of 2-oxobutyrate, 2-oxovalerate and...
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Design, synthesis, and molecular dynamics simulation studies of some novel kojic acid fused 2-amino-3-cyano-4H-pyran derivatives as tyrosinase inhibitors
A novel series of kojic acid fused 2-amino-3-cyano-4H-pyran derivatives were synthesized via a multicomponent reaction involving kojic acid,...
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Propensities of Some Amino Acid Pairings in α-Helices Vary with Length
The results of secondary structure prediction methods are widely used in applications in biotechnology and bioinformatics. However, the accuracy...
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Influence of the Nature of Amino Acids on the Formation of Supramolecular Complexes with Calixarenemethylene-bis-Phosphonic Acid
The formation of supramolecular complexes of 3-methyl-sulfido-propoxycalix[4]arene-methylene- bis -phosphonic acid with seventeen amino acids in...
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Molecular self-assembled helix peptide nanotubes based on some amino acid molecules and their dipeptides: molecular modeling studies
ContextThe paper considers the features of the structure and dipole moments of several amino acids and their dipeptides which play an important role...
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Investigation of molecular details of a bacterial cationic amino acid transporter (GkApcT) during arginine transportation using molecular dynamics simulation and umbrella sampling techniques
ContextCationic amino acid transporters (CATs) facilitate arginine transport across membranes and maintain its levels in various tissues and organs,...
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Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution
The discovery of crosstalk effects on the renin–angiotensin system (RAS) is limited by the lack of approaches to quantitatively monitor, in real...
