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Amino acid profiling and structural characterization of sorghum protein concentrates using enzyme liquefaction
Sorghum protein concentrate was produced from sorghum flour utilizing α-amylase treatment for starch liquefaction. A central composite design was...
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From the Prebiotic Synthesis of α-Amino Acids Towards a Primitive Translation Apparatus for the Synthesis of Peptides
The demonstration that ribosomal peptide synthesis is a ribozyme-catalyzed reaction does not establish that amino acids and peptides have been... -
Amino Acid Profile and Bioavailability of Plant-Based Protein-Rich Products
With a rising planetary population, and a growing consumer interest in alternative protein sources, understanding the nutritional value of... -
Reduced immunogenicity of β-lactoglobulin by single amino acid substitution
To reduce the immunogenicity of β-lactoglobulin (BLG), we prepared single amino acid substituted recombinant BLG mutants (BLG/P126A, BLG/V128D and...
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The structure and Hirshfeld surface analysis of the 4-amino 3-nitrobenzoic acid triclinic polymorph
By preparation of 4-amino-3-nitrobenzoic acid (4-A3NBA-P) in the triclinic crystal form in contrast to known monoclinic crystals polymorphism of this...
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Chemical Characterization of Apricot Kernel: Nutraceutical Composition, Amino Acid, and Fatty Acid Profile
Apricot kernels are valuable by-products of apricot processing industry known to have industrial applications. The present study reports the amino...
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Synthesis and Antibacterial Activity of Caffeine Derivatives Containing Amino-Acid Fragments
Cross-coupling of 8-bromocaffeine, 8-bromo-1-butyltheobromine, or 8-bromo-7-butyltheophylline with α -, β -, or ω -amino-acid methyl or t -butyl ester...
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Exploration of cellular uptake and endocytosis mechanisms for doxorubicin-loaded poly (amino acid) nanocarriers
This study revolves around the synthesis of poly (amino acid)-based polymers, specifically designed as block copolymers incorporating poly (glutamic...
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Amino acid analysis for peptide quantitation using reversed-phase liquid chromatography combined with multiple reaction monitoring mass spectrometry
Amino acid analysis (AAA) can be used for absolute quantitation of standard peptides after acid hydrolysis using 6 M HCl. Obtained individual amino...
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Fluorescent Proteins: Crystallization, Structural Determination, and Nonnatural Amino Acid Incorporation
Fluorescent proteins have revolutionized cell biology and cell imaging through their use as genetically encoded tags. Structural biology has been... -
Efficient synthesis of Ala-Tyr by L-amino acid ligase coupled with ATP regeneration system
The multi-enzyme coupling reaction system has become a promising biomanufacturing platform for biochemical production. Tyr is an essential amino...
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Nutritional properties and amino acid profile of buckwheat bread
The effect of replacement of wheat flour with buckwheat flour at levels of 10, 20, 30, 40, and 50% on nutritional, texture, and physicochemical...
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Preparation of Polymer-Based Amino Acid Stationary Phase and Its Application for Mixed-Mode Chromatography
Polymer microspheres have received attention because of their excellent properties. In this work, a polymer matrix zwitterionic amino acid stationary...
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Biochemical Characterization of a Marine Pseudoalteromonas citrea-Derived Fatty Acyl-AMP Ligase That Exhibits N-Acyl Amino Acid Synthetic Activity
Activation of fatty acids as acyl-adenylates by fatty acid-AMP ligase (FAAL) is a well-established process contributing to the formation of various...
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The Application of SDS-PAGE Protein and HPTLC Amino Acid Profiling for Verification of Declared Variety and Geographical Origin of Honey
Proteins and amino acids are minor components of honey that are rarely used for its quality evaluation, although these components create its...
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A novel green amino acid derivative hydrogel with multi-stimulus responsiveness
Even though amino acid derivatives are always used as the building blocks to construct gels in supramolecular chemistry, there is still no report...
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Intestinal mucosal microbiota mediate amino acid metabolism involved in the gastrointestinal adaptability to cold and humid environmental stress in mice
Growing evidence has demonstrated that cold and humid environmental stress triggers gastrointestinal (GI) disorders. In this study, we explored the...
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Electronic-Optical Properties of Tetraphenylporphyrin Derivatives Containing Amino Acid Fragments
AbstractThe complexing properties of 5-{4′-[2-amino-3-(4-hydroxyphenyl)propanamidophenyl]}-10,15,20-triphenylporphine, 5-{4′-[ N -( tert -butoxycarbonyl)...
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Modular enantioselective access to β-amino amides by Brønsted acid-catalysed multicomponent reactions
β - Amino acids are structural motifs widely found in therapeutic natural products, novel biomimetic polymers and peptidomimetics. As a convergent...
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Neuroprotective activity of selenium nanoparticles against the effect of amino acid enantiomers in Alzheimer’s disease
Alzheimer’s disease (AD), the most prevalent neurodegenerative disease, is characterized by extracellular accumulation of amyloid-beta protein (Aβ),...