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The resting serum metabolome in response to short-term sprint interval training
PurposeTo investigate the response of a targeted fraction of (168 metabolites) of the resting serum metabolome to 9 sessions of sprint interval...
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Short-term dietary changes can result in mucosal and systemic immune depression
Omnivorous animals, including mice and humans, tend to prefer energy-dense nutrients rich in fat over plant-based diets, especially for short periods...
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Short and long-term 2100 MHz radiofrequency radiation causes endoplasmic reticulum stress in rat testis
Long-term radiofrequency radiation (RFR) exposure, which adversely affects organisms, deteriorates testicular functions. Misfolding or unfolding...
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Temporal filters in response to presynaptic spike trains: interplay of cellular, synaptic and short-term plasticity time scales
Temporal filters, the ability of postsynaptic neurons to preferentially select certain presynaptic input patterns over others, have been shown to be...
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Short-term exposure to antibiotics begets long-term disturbance in gut microbial metabolism and molecular ecological networks
BackgroundAntibiotic exposure can occur in medical settings and from environmental sources. Long-term effects of brief antibiotic exposure in early...
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MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value
Treatment with the alkylating agent temozolomide is known to be prognostically beneficial in a subset of glioblastoma patients. Response to such...
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High-dose short-term osimertinib treatment is effective in patient-derived metastatic colorectal cancer organoids
BackgroundMost tyrosine kinase inhibitors (TKIs) have failed in clinical trials for metastatic colorectal cancer (mCRC). To leverage the additional...
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Long-term oral administration of curcumin is effective in preventing short-term memory deterioration and prolonging lifespan in a mouse model of Alzheimer’s disease
Curcumin (Curc) has been shown to have the potential to ameliorate or prevent the development of Alzheimer's disease (AD). However, most of them are...
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The gut microbiome modifies the associations of short- and long-term physical activity with body weight changes
BackgroundThe gut microbiome regulates host energy balance and adiposity-related metabolic consequences, but it remains unknown how the gut...
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The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk
ObjectiveCurrent breast cancer risk prediction scores and algorithms can potentially be further improved by including molecular markers. To this end,...
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Clinical characteristics and MRI based radiomics nomograms can predict iPFS and short-term efficacy of third-generation EGFR-TKI in EGFR-mutated lung adenocarcinoma with brain metastases
BackgroundPredicting short-term efficacy and intracranial progression-free survival (iPFS) in epidermal growth factor receptor gene mutated...
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Delivery and short-term maternal and fetal safety of vaginally administered PEG-PLGA nanoparticles
At the onset of pregnancy, people with preexisting conditions face additional challenges in carrying their pregnancy to term, as the safety of the...
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Ameliorative effects of Fingolimod (FTY720) on microglial activation and psychosis-related behavior in short term cuprizone exposed mice
Schizophrenia is a psychiatric disorder that affects around 1% of the population in widespread populations, with severe cases leading to long-term...
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Risk factors for short-term prognosis of end-stage liver disease complicated by invasive pulmonary aspergillosis
Background and aimPatients with end-stage liver disease (ESLD) are susceptible to invasive pulmonary aspergillosis (IPA). This study aimed to...
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Short-term response might influence the treatment-related benefit of adjuvant chemotherapy after concurrent chemoradiotherapy for esophageal squamous cell carcinoma patients
BackgroundWhether adjuvant chemotherapy (AC) after concurrent chemoradiotherapy (CCRT) could provide benefit to esophageal squamous cell carcinoma...
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Effects of short-term repeated sprint training in hypoxia or with blood flow restriction on response to exercise
This study compared the effects of a brief repeated sprint training (RST) intervention performed with bilateral blood flow restriction (BFR)...
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The Coordinating Role of the Actin Cytoskeleton in Short-Term Neural Network Plasticity Involving Excitatory and Inhibitory Synapses
The problem of frequency coding is closely related to studies of the mechanisms by which inhibitory interneurons are involved in neural network...
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Short-term inhalation exposure to cigarette smoke induces oxidative stress and inflammation in lungs without systemic oxidative stress in mice
Smoking is a well-established risk factor for various pathologies, including pulmonary diseases, cardiovascular disorders, and cancers. The toxic...
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Short-term intensive fasting enhances the immune function of red blood cells in humans
BackgroundFasting is known to influence the immune functions of leukocytes primarily by regulating their mobilization and redistribution between the...
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The right uncinate fasciculus supports verbal short-term memory in aphasia
Verbal short-term memory (STM) deficits are associated with language processing impairments in people with aphasia. Importantly, the integrity of STM...
