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Placental neutrophil reverse trans-migration and maternal serum neutrophil extracellular trap expression in HIV infection co-morbid pre-eclampsia in women of African ancestry
Neutrophil extracellular traps (NETs) and placental neutrophil reverse transmigration (r-TM) are implicated in the pathogenesis of pre-eclampsia...
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Visualizing NETosis Using a Novel Neutrophil Extracellular Trap-Specific Marker
As the most abundant leukocyte in circulation, the neutrophil plays a far-reaching role in maintaining homeostasis. Within the context of disease,...
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Neutrophils and neutrophil extracellular traps in oral health and disease
Neutrophils perform essential functions in antimicrobial defense and tissue maintenance at mucosal barriers. However, a dysregulated neutrophil...
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Neutrophil reverse migration
The behavior of neutrophils is very important for the resolution of inflammation and tissue repair. People have used advanced imaging techniques to...
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Neutrophil diversity and plasticity: Implications for organ transplantation
Neutrophils, as the first defenders against external microbes and stimuli, are highly active and finely regulated innate immune cells. Emerging...
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Membrane potential dynamics of C5a-stimulated neutrophil granulocytes
Neutrophil granulocytes play a crucial role in host defense against invading pathogens and in inflammatory diseases. The aim of this study was to...
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Transient receptor potential melastatin 2 regulates neutrophil extracellular traps formation and delays resolution of neutrophil-driven sterile inflammation
The formation of neutrophil extracellular traps (NETs) is a process releasing into the extracellular space networks of chromatin fibers decorated...
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Strategies of neutrophil diversification
Neutrophils are formidable defenders. Their vast numbers, constant production, high cytotoxicity and capacity to produce extracellular traps,...
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Flow Cytometry for Measuring Neutrophil Function
Neutrophils are crucial cells for host defence. In particular, their phagocytic function is a major mechanism through which the immune system...
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Neutrophil-Derived S100A8/A9 in Cardiovascular Disease and Beyond
Purpose of ReviewIncrease in neutrophil counts that are associated with cardiovascular risk factors including myocardial infarction (MI) and early...
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Effects of neutrophil fate on inflammation
IntroductionNeutrophils are important participants in the innate immune response. They rapidly and efficiently identify and clear infectious agents...
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Neutrophil extracellular traps in intracerebral hemorrhage: implications for pathogenesis and therapeutic targets
Intracerebral hemorrhage is a common neurological disease, and its pathological mechanism is complex. As the first recruited leukocyte subtype after...
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GPR84 regulates pulmonary inflammation by modulating neutrophil functions
Acute lung injury (ALI) is an acute, progressive hypoxic respiratory failure that could develop into acute respiratory distress syndrome (ARDS) with...
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Neutrophil sub-types in maintaining immune homeostasis during steady state, infections and sterile inflammation
IntroductionNeutrophils are component of innate immune system and a) eliminate pathogens b) maintain immune homeostasis by regulating other immune...
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The Effect of Vitamin D3 on Neutrophil Extracellular Trap Formation in High-Glucose Conditions
NETosis, i.e ., the formation of neutrophil extracellular traps (NET), and neutrophil autophagy are important elements in the pathogenesis and the...
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Colchicine Alleviates Rosacea by Inhibiting Neutrophil Inflammation Activated by the TLR2 Pathway
Rosacea is a chronic facial inflammatory skin disease that occurs with dysfunction of the immune system. Colchicine was reported to have...
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Modeling Ventilator-Induced Lung Injury and Neutrophil Infiltration to Infer Injury Interdependence
Acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI) are heterogeneous conditions. The spatiotemporal evolution of...
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Role of Nitric Oxide Synthase and Nitric Oxide Signaling in the Neutrophil Ontogeny and Functions
Neutrophils are the essential guards of the immune system that inactivate different pathogens as well as instruct specific immune responses. Nitric...
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Vascular smooth muscle cells in response to cholesterol crystals modulates inflammatory cytokines release and promotes neutrophil extracellular trap formation
BackgroundThe formation and accumulation of cholesterol crystals (CC) at the lesion site is a hallmark of atherosclerosis. Although studies have...
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Neutrophil extracellular traps promote acetaminophen-induced acute liver injury in mice via AIM2
Excessive acetaminophen (APAP) can induce neutrophil activation and hepatocyte death. Along with hepatocyte dysfunction and death, NETosis (a form of...
