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Mitochondrial and Metabolic Drivers of Pulmonary Vascular Endothelial Dysfunction in Pulmonary Hypertension
Pulmonary hypertension (PH) is a deadly and increasingly prevalent vascular disease characterized by excessive pulmonary vascular remodeling and... -
Glutamate neurotoxicity: Perturbations of ionic homeostasis, mitochondrial dysfunction, and changes in cell functioning
The hyperstimulation of neuronal glutamate receptors during different pathologies results in CNS injuries. This review summarizes the data concerning...
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Cellular Membrane Transport Mechanisms
The lipid bilayer is very poorly permeable to water-soluble (hydrophilic), and even more so to charged, molecules. The permeabilities measured in... -
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Deutsche Pharmakologische Gesellschaft
Problem 1) Maximum unknown, baseline increased, drug effects overadditively enhanced: the examination of dose response curves of...