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Laboratory Diagnosis of Bacterial Diseases
The clinical manifestations of bacterial diseases may be non-specific and protean. Nevertheless, they provide a clue in the diagnosis of bacterial...
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Laboratory Diagnosis of Viral Diseases
The clinical manifestations may be protean and nonspecific for many of the viral infections. However, they provide a clue in diagnosing viral...
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Laboratory Diagnosis of HEV Infection
Serological and nucleic acid tests for detecting hepatitis E virus (HEV) have been developed for both epidemiologic and diagnostic purposes. The...
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Laboratory Diagnosis of Tuberculosis
The diagnosis of tuberculosis (TB) is multifaceted. It requires an integrated approachApproachintegrated that extends to all facets resulting in...
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Role of the Laboratory in the Diagnosis of Poxvirus Infections
Although WHO-led global efforts led to eradication of smallpoxSmallpox over four decades ago, other poxvirusesPoxvirus, especially monkeypoxMonkeypox...
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First field and laboratory evaluation of LAMP assay for malaria diagnosis in Cubal, Angola
BackgroundMalaria is a globally distributed infectious disease. According to the World Health Organization, Angola is one of the six countries that...
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Pediatric Tuberculosis: Current Evidence for Laboratory Diagnosis
As children develop paucibacillary forms of tuberculosis (TB), bacteriological tests usually are negative. This chapter describes aspects of the...
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Confirmatory Assay for Laboratory Diagnosis of Malaria Using Molecular Approach
BackgroundPrompt malarial treatment and surveillance is crucial for accurate diagnosis of Plasmodium Sp. Gold standard microscopic examination has...
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An algorithm for visceral leishmaniasis diagnosis in Brazil from a 10-year analysis of National Reference Laboratory data
Visceral leishmaniasis (VL) requires diagnostic assays to complement clinical suspicion. However, there is no standardization of a diagnostic flow...
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Competency of malaria laboratory diagnosis at national and provincial levels at the beginning of malaria post-elimination phase, China
BackgroundQualified malaria diagnosis competency has contributed to the great achievement of malaria elimination in China. After eliminating malaria,...
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Laboratory Diagnosis
The classic algorithm for diagnosing infection with the hepatitis C virus (HCV) requires screening of serum or plasma for HCV antibody followed by...
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Monkeypox Diagnosis in Clinical Settings: A Comprehensive Review of Best Laboratory Practices
An outbreakOutbreak of monkeypox (Mpox) was reported in more than 40 countries in early 2022. Accurate diagnosisDiagnosis of MpoxMpox can be...
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Celomic Fluid: Laboratory Workflow for Prenatal Diagnosis of Monogenic Diseases
BackgroundCelomic fluid can be considered as an ultra-filtrate of maternal serum, containing a high protein concentration, urea, and many other...
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Laboratory Evaluation of Thrombophilia
Venous thromboembolism (VTE) occurs typically in the veins of the lower extremities and/or as pulmonary embolism. There is a myriad of causes of VTE...
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Building pathology capacity in sub-Saharan Africa to improve breast cancer diagnosis and treatment: training laboratory technicians in high-quality manual immunohistochemistry
BackgroundTo address the need for a skilled workforce in breast cancer (BC) pathology in sub-Saharan Africa (SSA), we implemented an education...
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Historical Laboratory Contributions Supporting Rabies Diagnosis and Disease Prevention and Control in the Americas
Rabies was one of the first documented diseases in history. However, rapid, sensitive and specific methods of detection of the viral etiological...
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ANA-specific antibodies, ANA patterns, anti-ds-DNA results, and clinical diagnosis: a laboratory and clinical audit
The diagnosis of systemic autoimmune diseases (SAID) is challenging, due to overlap** features with other non-immune disorders. Anti-nuclear...
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An Overview of Laboratory Testing for ADAMTS13
ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) is also called von Willebrand factor (VWF) cleaving...
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Microfluidic Systems for Cancer Diagnosis
This detailed volume explores recent developments in microfluidics technologies for cancer diagnosis and monitoring. The book is divided into two...
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Laboratory Diagnosis of Dermatophytosis
Dermatophytoses are a very common cause of consultation in dermatology. The diagnosis of these superficial infections, which include a large variety...