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An economon model of drug addiction
The term “economon” (i:’ka.nə.muhn; plural: economa) is introduced here to describe an economic unit composed of two participants engaged in mutually...
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Goal-Directed and Habitual Control in Human Drug Addiction
Learning theory has proposed that everyday actions are controlled by at least two dissociable systems: one that governs deliberate goal-directed...
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Interaction Between Habitual and Goal-Directed Processes in Addiction
Are individuals suffering from addiction in control of their drug use behavior, and is this control habitual or goal-directed? The habit theory of...
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Drug Addiction and Drug Dependency
Drug abuse and dependency liability assessments are important components of the discovery, development, and evaluation of novel drug entities and are...
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Drug Addiction in Cancer
One of the main changes that occur as a consequence of cancer genetic and epigenetic alterations is represented by transcriptional deregulation....
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Toll-Like Receptor 4: A Novel Target to Tackle Drug Addiction?
Drug addiction is a chronic brain disease characterized by compulsive drug-seeking and drug-taking behaviors despite the major negative consequences....
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Heterogeneity in choice models of addiction: the role of context
RationaleTheories of addiction guide scientific progress, funding priorities, and policy development and ultimately shape how people experiencing or...
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The Genetically Informed Neurobiology of Addiction (GINA) model
Addictions are heritable and unfold dynamically across the lifespan. One prominent neurobiological theory proposes that substance-induced changes in...
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Glutamatergic neurons in ventral pallidum modulate heroin addiction via epithalamic innervation in rats
Glutamatergic neurons in ventral pallidum (VP Glu ) were recently reported to mediate motivational and emotional behavior, but its role in opioid...
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Food Addiction
For years, the concept of food addiction has been gaining increased attention in the scientific literature and the media. A conceptualization of the...
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Food Addiction
Throughout history, people were concerned with eating sufficiently to survive and reproduce. It is only recently with the advent of the modern food...
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Psyche and Mental Illness: Addiction
In this chapter we deal with the topic of addiction: first with the question of the occurrence of addiction, the diagnostic classification and the...
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DNA replication stress and mitotic catastrophe mediate sotorasib addiction in KRASG12C-mutant cancer
BackgroundSotorasib is the first KRAS G12C inhibitor approved by the US Food and Drug Administration for treating KRAS G12C -mutant non-small-cell lung...
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Internet Addiction
As Internet addiction is becoming more prevalent around the world, it has attracted considerable scientific and public attention. The present chapter...
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Internet Addiction
As Internet addiction is becoming more prevalent around the world, it has attracted considerable scientific and public attention. The present chapter...
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The Periaqueductal Gray and Its Extended Participation in Drug Addiction Phenomena
The periaqueductal gray (PAG) is a complex mesencephalic structure involved in the integration and execution of active and passive self-protective...
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Behind the ChatGPT Hype: Are Its Suggestions Contributing to Addiction?
ChatGPT has been a frequent topic of discussion lately. All over the Internet, from YouTube to blogs, there have been reports about how ChatGPT is...
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Pharmacogenetics of Addiction Therapy
Drug addiction is a serious relapsing disease that has high costs to society and to the individual addicts. Treatment of these addictions is still in...
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A comparative study of religious beliefs, spiritual intelligence and spiritual well-being in two therapies based on education (anonymous drug user) and methadone in drug user in Iran
ObjectivePrevention of high-risk behaviors has always been considered; According to the researches, a person’s religious attitudes and beliefs and...
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Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition
The amygdala processes positive and negative valence and contributes to addiction, but the cell-type-specific gene regulatory programs involved are...
