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A mediation analysis framework based on variance component to remove genetic confounding effect
Identification of pleiotropy at the single nucleotide polymorphism (SNP) level provides valuable insights into shared genetic signals among...
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Unraveling phenotypic variance in metabolic syndrome through multi-omics
Complex multi-omics effects drive the clustering of cardiometabolic risk factors, underscoring the imperative to comprehend how individual and...
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Appropriate margin for planning target volume for breast radiotherapy during deep inspiration breath-hold by variance component analysis
BackgroundThis study aimed to quantify errors by using a cine electronic portal imaging device (cine EPID) during deep inspiration breath-hold (DIBH)...
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Individual Variance in Human Aggression: A Combined Effect of Polygenic Score and Social/Lifestyle Factors
AbstractTo date, the assessment of a simultaneous effect of SNPs on manifesting aggression via polygenic score (PGS) approach has been performed...
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Dimensionality reduction beyond neural subspaces with slice tensor component analysis
Recent work has argued that large-scale neural recordings are often well described by patterns of coactivation across neurons. Yet the view that...
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Brain fiber structure estimation based on principal component analysis and RINLM filter
Diffusion magnetic resonance imaging is a technique for non-invasive detection of microstructure in the white matter of the human brain, which is...
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Selection for environmental variance shifted the gut microbiome composition driving animal resilience
BackgroundUnderstanding how the host’s microbiome shapes phenotypes and participates in the host response to selection is fundamental for...
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Heritability and variance components of seed size in wild species: influences of breeding design and the number of genotypes tested
Seed size affects individual fitness in wild plant populations, but its ability to evolve may be limited by low narrow-sense heritability ( h 2 ). h 2 is...
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Assessment of two statistical approaches for variance genome-wide association studies in plants
Genomic loci that control the variance of agronomically important traits are increasingly important due to the profusion of unpredictable...
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Heritability and recursive influence of host genetics on the rumen microbiota drive body weight variance in male Hu sheep lambs
BackgroundHeritable rumen microbiota is an important modulator of ruminant growth performance. However, no information exists to date on host...
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Temporal and genomic analysis of additive genetic variance in breeding programmes
Genetic variance is a central parameter in quantitative genetics and breeding. Assessing changes in genetic variance over time as well as the genome...
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Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses
Nowadays medulloblastoma (MB) tumors can be treated with risk-stratified approaches with up to 80% success rate. However, disease relapses occur in...
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Principal Component Analysis of Grasp Force and Pose During In-Hand Manipulation
PurposeThe manner in which healthy humans interact with objects as they move them within the hand is essential for activities of everyday life. The...
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Differential effects of steroid hormones on levels of broad-sense heritability in a wild bird: possible mechanism of environment × genetic variance interaction?
Genetic variation is one of the key concepts in evolutionary biology and an important prerequisite of evolutionary change. However, we know very...
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Transcranial Direct Current Electrical Stimulation Modulates the Feedback-Related Negativity Component in a Monetary Game
The present study addressed the neurophysiological effects of transcranial direct current stimulation (tDCS) on a component of evoked potentials...
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Description of Divergence of Subpopulations in the Hierarchical System When Analyzing Isonymy: I. Variance as an Indicator of Divergence
AbstractMetapopulations typical of human populations with hierarchical subdivision into parts (subpopulations) corresponding to the classification of...
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Iterative principal component analysis method for improvised classification of breast cancer disease using blood sample analysis
Breast cancer is the most common cancer in women occurring worldwide. Some of the procedures used to diagnose breast cancer are mammogram, breast...
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Tracking the Reliability of Force Plate-Derived Countermovement Jump Metrics Over Time in Female Basketball Athletes: A Comparison of Principal Component Analysis vs. Conventional Methods
BackgroundEstablishing the reliability of countermovement jump (CMJ) metrics over multiple weeks can be important in understanding and tracking...
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Extraction and Digitization of ECG Signals from Standard Clinical Portable Document Format Files for the Principal Component Analysis of T-wave Morphology
Introduction: T-wave analysis from standard electrocardiogram (ECG) remains one of the most available clinical and research methods for evaluating...
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Using principal component analysis to determine which vestibular stimuli provide best biomarkers for separating Alzheimer’s from mixed Alzheimer’s disease
Alzheimer’s disease (AD) is often mixed with cerebrovascular disease (AD-CVD). Heterogeneity of dementia etiology and the overlap** of...