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  1. A mediation analysis framework based on variance component to remove genetic confounding effect

    Identification of pleiotropy at the single nucleotide polymorphism (SNP) level provides valuable insights into shared genetic signals among...

    Zihan Dong, Hongyu Zhao, Andrew T. DeWan in Journal of Human Genetics
    Article 25 March 2024
  2. Unraveling phenotypic variance in metabolic syndrome through multi-omics

    Complex multi-omics effects drive the clustering of cardiometabolic risk factors, underscoring the imperative to comprehend how individual and...

    Lamessa Dube Amente, Natalie T Mills, ... S. Hong Lee in Human Genetics
    Article 14 December 2023
  3. Appropriate margin for planning target volume for breast radiotherapy during deep inspiration breath-hold by variance component analysis

    Background

    This study aimed to quantify errors by using a cine electronic portal imaging device (cine EPID) during deep inspiration breath-hold (DIBH)...

    Yuka Ono, Michio Yoshimura, ... Takashi Mizowaki in Radiation Oncology
    Article Open access 06 March 2021
  4. Individual Variance in Human Aggression: A Combined Effect of Polygenic Score and Social/Lifestyle Factors

    Abstract

    To date, the assessment of a simultaneous effect of SNPs on manifesting aggression via polygenic score (PGS) approach has been performed...

    A. V. Kazantseva, Yu. D. Davydova, ... E. K. Khusnutdinova in Russian Journal of Genetics
    Article 01 December 2023
  5. Dimensionality reduction beyond neural subspaces with slice tensor component analysis

    Recent work has argued that large-scale neural recordings are often well described by patterns of coactivation across neurons. Yet the view that...

    Arthur Pellegrino, Heike Stein, N. Alex Cayco-Gajic in Nature Neuroscience
    Article Open access 06 May 2024
  6. Brain fiber structure estimation based on principal component analysis and RINLM filter

    Diffusion magnetic resonance imaging is a technique for non-invasive detection of microstructure in the white matter of the human brain, which is...

    Yuemin Zhu, Yuanjun Wang in Medical & Biological Engineering & Computing
    Article 23 November 2023
  7. Selection for environmental variance shifted the gut microbiome composition driving animal resilience

    Background

    Understanding how the host’s microbiome shapes phenotypes and participates in the host response to selection is fundamental for...

    Cristina Casto-Rebollo, María José Argente, ... Noelia Ibáñez-Escriche in Microbiome
    Article Open access 04 July 2023
  8. Heritability and variance components of seed size in wild species: influences of breeding design and the number of genotypes tested

    Seed size affects individual fitness in wild plant populations, but its ability to evolve may be limited by low narrow-sense heritability ( h 2 ). h 2 is...

    Eugenio Larios, Tadeo H. Ramirez-Parada, Susan J. Mazer in Heredity
    Article 14 February 2023
  9. Assessment of two statistical approaches for variance genome-wide association studies in plants

    Genomic loci that control the variance of agronomically important traits are increasingly important due to the profusion of unpredictable...

    Matthew D. Murphy, Samuel B. Fernandes, ... Alexander E. Lipka in Heredity
    Article 10 May 2022
  10. Heritability and recursive influence of host genetics on the rumen microbiota drive body weight variance in male Hu sheep lambs

    Background

    Heritable rumen microbiota is an important modulator of ruminant growth performance. However, no information exists to date on host...

    Weimin Wang, Yukun Zhang, ... Fadi Li in Microbiome
    Article Open access 29 August 2023
  11. Temporal and genomic analysis of additive genetic variance in breeding programmes

    Genetic variance is a central parameter in quantitative genetics and breeding. Assessing changes in genetic variance over time as well as the genome...

    Letícia A. de C. Lara, Ivan Pocrnic, ... Gregor Gorjanc in Heredity
    Article Open access 15 December 2021
  12. Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses

    Nowadays medulloblastoma (MB) tumors can be treated with risk-stratified approaches with up to 80% success rate. However, disease relapses occur in...

    Konstantin Okonechnikov, Aniello Federico, ... Andrey Korshunov in Acta Neuropathologica Communications
    Article Open access 12 January 2023
  13. Principal Component Analysis of Grasp Force and Pose During In-Hand Manipulation

    Purpose

    The manner in which healthy humans interact with objects as they move them within the hand is essential for activities of everyday life. The...

    Dipayan Das, Joshua Schultz in Journal of Medical and Biological Engineering
    Article 07 September 2022
  14. Differential effects of steroid hormones on levels of broad-sense heritability in a wild bird: possible mechanism of environment × genetic variance interaction?

    Genetic variation is one of the key concepts in evolutionary biology and an important prerequisite of evolutionary change. However, we know very...

    Szymon M. Drobniak, Joanna Sudyka, ... Katarzyna Janas in Heredity
    Article 17 December 2021
  15. Transcranial Direct Current Electrical Stimulation Modulates the Feedback-Related Negativity Component in a Monetary Game

    The present study addressed the neurophysiological effects of transcranial direct current stimulation (tDCS) on a component of evoked potentials...

    A. A. Gorin, V. A. Klyuchnikov, ... A. N. Shestakova in Neuroscience and Behavioral Physiology
    Article 01 March 2023
  16. Description of Divergence of Subpopulations in the Hierarchical System When Analyzing Isonymy: I. Variance as an Indicator of Divergence

    Abstract

    Metapopulations typical of human populations with hierarchical subdivision into parts (subpopulations) corresponding to the classification of...

    V. P. Passekov in Russian Journal of Genetics
    Article 25 June 2022
  17. Iterative principal component analysis method for improvised classification of breast cancer disease using blood sample analysis

    Breast cancer is the most common cancer in women occurring worldwide. Some of the procedures used to diagnose breast cancer are mammogram, breast...

    Geetharamani R, Sivagami G in Medical & Biological Engineering & Computing
    Article 31 July 2021
  18. Tracking the Reliability of Force Plate-Derived Countermovement Jump Metrics Over Time in Female Basketball Athletes: A Comparison of Principal Component Analysis vs. Conventional Methods

    Background

    Establishing the reliability of countermovement jump (CMJ) metrics over multiple weeks can be important in understanding and tracking...

    Joshua A. J. Keogh, Chris Bishop, ... Dylan Kobsar in Journal of Science in Sport and Exercise
    Article 15 August 2023
  19. Extraction and Digitization of ECG Signals from Standard Clinical Portable Document Format Files for the Principal Component Analysis of T-wave Morphology

    Introduction

    : T-wave analysis from standard electrocardiogram (ECG) remains one of the most available clinical and research methods for evaluating...

    Michal Schäfer, Max B. Mitchell, ... Johannes C. von Alvensleben in Cardiovascular Engineering and Technology
    Article 25 July 2023
  20. Using principal component analysis to determine which vestibular stimuli provide best biomarkers for separating Alzheimer’s from mixed Alzheimer’s disease

    Alzheimer’s disease (AD) is often mixed with cerebrovascular disease (AD-CVD). Heterogeneity of dementia etiology and the overlap** of...

    S. Marzban, Z. Dastgheib, ... Z. Moussavi in Medical & Biological Engineering & Computing
    Article 13 May 2024
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