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Dynamic Coronary Blood Flow Velocity and Wall Shear Stress Estimation Using Ultrasound in an Ex Vivo Porcine Heart
PurposeWall shear stress (WSS) is a critically important physical factor contributing to atherosclerosis. Map** the spatial distribution of local,...
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Association between expiratory mouth pressure and abdominal muscle activity in healthy young males
PurposeTo clarify the association between forced expiration and the abdominal muscles by assessing the relationship between expiratory mouth pressure...
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A State-Of-The-Art Review on Coronary Artery Border Segmentation Algorithms for Intravascular Ultrasound (IVUS) Images
Intravascular Ultrasound images (IVUS) is a useful guide for medical practitioners to identify the vascular status of coronary arteries in human...
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A Dynamic Sheep Model to Induce Pulmonary Hypertension and Right Ventricular Failure
Decompensated right ventricular failure (RVF) in pulmonary hypertension (PH) is fatal, with limited medical treatment options. Develo** and testing...
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Wnt16 Increases Bone-to-Implant Contact in an Osteopenic Rat Model by Increasing Proliferation and Regulating the Differentiation of Bone Marrow Stromal Cells
Osseointegration is a complex biological cascade that regulates bone regeneration after implant placement. Implants possessing complex multiscale...
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Ultrasound-mediated blood–brain barrier opening uncovers an intracerebral perivenous fluid network in persons with Alzheimer’s disease
BackgroundFocused ultrasound (FUS)-mediated blood–brain barrier (BBB) opening is under investigation as a therapeutic modality for neurodegeneration,...
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Patch Clamp Technology for Focused Ultrasonic (FUS) Neuromodulation
Electrical stimulation of neural tissue, such as deep brain stimulation (DBS) and cortical stimulation, is widely applied therapeutic neuromodulation...
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Physiological Assessment of Muscle, Heart, and Whole Body Function in the Canine Model of Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by dystrophin deficiency. Patients gradually lose motor function, become...
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Swine Model of Myocardial Infarction Induced by Ischemia-Reperfusion and Embolization
Acute myocardial infarction continues to account for a growing burden of heart failure worldwide. Despite existing therapies, new approaches for...
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The Interleukin-8 Pathway in Cancer
Interleukin-8 (IL-8), a pro-inflammatory chemotactic cytokine encoded by the CXCL8 gene, is mainly released by macrophages and other immune cells and...
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Rib detection using pitch-catch ultrasound and classification algorithms for a novel ultrasound therapy device
BackgroundNoninvasive ultrasound (US) has been used therapeutically for decades, with applications in tissue ablation, lithotripsy, and physical...
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Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma: Dosimetric consequences on non-coplanar IMRT as initial results from a phase I trial
BackgroundGlioblastoma is a rapidly proliferating tumor. Patients bear an inferior prognosis with a median survival time of 14-16 months....
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Obstructive sleep apnea improves with non-invasive hypoglossal nerve stimulation using temporal interference
BackgroundPeripheral nerve stimulation is used in both clinical and fundamental research for therapy and exploration. At present, non-invasive...
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Using Operant Reach Chambers to Assess Mouse Skilled Forelimb Use After Stroke
Skilled forelimb reaching and gras** are important components of rodent motor performance. The isometric pull task can serve as a tool for...
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Treatment-Emergent Central Sleep Apnea (TECSA) with Chronic Use of Mandibular Advancement Device (MAD): A Case Series
PurposeExisting studies on TECSA with MAD usage suggests that TECSA occurs only during the initial MAD treatment and resolves with no long-term...
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Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model
BackgroundSystemic drug delivery to the central nervous system is limited by presence of the blood–brain barrier (BBB). Low intensity focused...
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Ultrasound of the Reproductive System
This chapter reviews the basic anatomy and physiology of adult male and female reproduction, including the regulation of physiological functions by...
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Development of a biodegradable polymer-based implant to release dual drugs for post-operative management of cataract surgery
Cataract surgery is followed by post-operative eye drops for a duration of 4–6 weeks. The multitude of ocular barriers, coupled with the discomfort...
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Assessment of thoracic spinal curvatures in static postures using spatially tracked 3D ultrasound volumes: a proof-of-concept study
The assessment of spinal posture is a difficult endeavour given the lack of identifiable bony landmarks for placement of skin markers. Moreover,...
