Search
Search Results
-
A multicenter noninferior randomized controlled study of sentinel lymph node biopsy alone versus sentinel lymph node biopsy plus lymphadenectomy for patients with stage I endometrial cancer, INSEC trial concept
BackgroundUp to the present time, there has remained a lack of strong evidence as to whether sentinel lymph node biopsy can replace lymphadenectomy...
-
Selective omission of sentinel lymph node biopsy in mastectomy for ductal carcinoma in situ: identifying eligible candidates
BackgroundSentinel lymph node biopsy (SLNB) is recommended for patients with ductal carcinoma in situ (DCIS) undergoing mastectomy, given the...
-
Sentinel Lymph Node Biopsy in Breast Cancer
Lymphatic metastasis is a strong predictor of poor outcome in breast cancer patients. Most often, lymphatic metastasis occurs through the axillary...
-
Sentinel Lymph Node Biopsy for Primary Cutaneous Malignancy
Sentinel lymph node biopsy (SLNB) is the international standard of care for providing prognostic information in cutaneous melanoma. This chapter...
-
Magnetic procedure for sentinel lymph node detection and evaluation of metastases: design and rationale of the Lowmag trial
BackgroundPrimary tumour biology and axillary lymph node status are key prognostic factors in breast cancer treatment. The LowMag trial introduced a...
-
Sentinel lymph nodes in melanoma: necessary as ever for optimal treatment
Lymphatic metastasis is the dominant route of initial spread for most solid tumors. For many such malignancies, including melanomas, surgical...
-
Advantages of contrast-enhanced ultrasound in the localization and diagnostics of sentinel lymph nodes in breast cancer
Sentinel lymph nodes (SLNs) are the first station of lymph nodes that extend from the breast tumor to the axillary lymphatic drainage. The...
-
Sentinel lymph node biopsy in melanoma: beyond histologic factors
Sentinel lymph node (SLN) biopsy should be performed with the technical expertise required to correctly identify the sentinel node, in the context of...
-
Outcomes of sentinel node biopsy according to MRI response in an association with the subtypes in cN1–3 breast cancer after neoadjuvant systemic therapy, multicenter cohort study
BackgroundThis study investigated the feasibility of sentinel lymph node biopsy (SLNB) after neoadjuvant systemic therapy (NAST) in patients with...
-
Reprogramming of sentinel lymph node microenvironment during tumor metastasis
Metastasis is a major cause of death in patients with cancer. The two main routes for cancer cell dissemination are the blood and lymphatic systems....
-
The role of sentinel node tumor burden in modeling the prognosis of melanoma patients with positive sentinel node biopsy: an Italian melanoma intergroup study (N = 2,086)
BackgroundThe management of melanoma patients with metastatic melanoma in the sentinel nodes (SN) is evolving based on the results of trials...
-
Sentinel Lymph Node Map** in Non-small Cell Lung, Colon, and Thyroid Carcinomas
Lymphatic map** and sentinel lymph node (SLN) biopsy is now a standard procedure for melanoma and breast cancer, providing the most accurate...
-
Multi-center study on predicting breast cancer lymph node status from core needle biopsy specimens using multi-modal and multi-instance deep learning
The objective of our study is to develop a deep learning model based on clinicopathological data and digital pathological image of core needle biopsy...
-
Exploratory analysis of lateral pelvic sentinel lymph node status for optimal management of laparoscopic lateral lymph node dissection in advanced lower rectal cancer without suspected lateral lymph node metastasis
BackgroundTotal mesorectal excision (TME) and lateral lymph node dissection (LLND) without radiotherapy (RT) are standard treatment for lower cT3/4...
-
Sentinel Node Navigation Surgery for Upper Gastrointestinal Cancer
Radical resection with systematic lymph node dissection is traditionally performed in patients with upper gastrointestinal cancer because the...
-
Retrospective validation study of an artificial neural network-based preoperative decision-support tool for noninvasive lymph node staging (NILS) in women with primary breast cancer (ISRCTN14341750)
BackgroundSurgical sentinel lymph node biopsy (SLNB) is routinely used to reliably stage axillary lymph nodes in early breast cancer (BC). However,...
-
Pathologic Assessment of Lymph Node Metastasis
The pathologic assessment and evaluation of lymph node status plays a central role in the diagnosis, staging, and management of most malignancies....
-
The value of preoperative sentinel lymph node contrast-enhanced ultrasound for breast cancer: a large, multicenter trial
ObjectiveThe study conducted a multicenter study in China to explore the learning curve of contrast enhanced ultrasound (CEUS) for sentinel lymph...
-
Sentinel lymph node map** with superparamagnetic iron oxide for melanoma: a pilot study in healthy participants to establish an optimal MRI workflow protocol
BackgroundCurrent pre-operative Sentinel Lymph Node (SLN) map** using dual tracing is associated with drawbacks (radiation exposure, logistic...
-
Sentinel lymph node procedure in patients with recurrent vulvar squamous cell carcinoma: a proposed protocol for a multicentre observational study
BackgroundStandard groin treatment in recurrent vulvar cancer consists of uni- or bilateral inguinofemoral lymphadenectomy (IFL), whereas in the...
