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PFASs–restriction proposal commentary on ECHA’s Annex XV restriction report, proposal for a restriction, March 2023
PFASs are defined as substances that contain at least one fully fluorinated methyl (CF 3 –) or methylene (–CF 2 –) carbon atom. The excellent technical...
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Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor
Human immunodeficiency virus (HIV) and other lentiviruses adapt to new hosts by evolving to evade host-specific innate immune proteins that differ in...
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Transient global amnesia and hippocampal diffusion restriction: an overlooked radiological finding
Transient global amnesia (TGA) is characterized by isolated sudden anterograde amnesia. Diffusion restriction can be observed in the hippocampus on...
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Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells
BackgroundSAMHD1 is a deoxynucleotide triphosphohydrolase that restricts replication of HIV-1 in differentiated leucocytes. HIV-1 is not restricted...
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Blood flow restriction augments the cross-education effect of isometric handgrip training
IntroductionThe application of blood flow restriction (BFR) to low-intensity exercise may be able to increase strength not only in the trained limb...
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Epigenetics Beyond Fetal Growth Restriction: A Comprehensive Overview
Fetal growth restriction is a pathological condition occurring when the fetus does not reach the genetically determined growth potential. The...
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Indicators of LPO and Antioxidant Protection in Rats During Long-Term Restriction of Motor Activity
This article presents a comprehensive study of the parameters of LPO (concentrations of malondialdehyde, diene conjugates, and intensity of...
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Impaired influenza A virus replication by the host restriction factor SAMHD1 which inhibited by PA-mediated dephosphorylation of the host transcription factor IRF3
BackgroundInfluenza A virus (IAV) can cause severe and life-threatening illness in humans and animals. Therefore, it is important to search for host...
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A validated restriction enzyme ddPCR cg05575921 (AHRR) assay to accurately assess smoking exposure
Background & MethodsIn this study, a novel restriction enzyme (RE) digestion-based droplet digital polymerase chain reaction (ddPCR) assay was...
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Intertemporal Decision-making and Risk Decision-making Among Habitual Nappers Under Nap Sleep Restriction: A Study from ERP and Time-frequency
Sleep restriction affects people’s decision-making behavior. Nap restriction is a vital subtopic within sleep restriction research. In this study, we...
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Sleep restriction reduces voluntary isometric quadriceps strength through reduced neuromuscular efficiency, not impaired contractile performance
Acute sleep restriction (SR) reduces strength through an unknown mechanism. Purpose: To determine how SR affects quadriceps contractile function and...
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Sex differences in response to obesity and caloric restriction on cognition and hippocampal measures of autophagic-lysosomal transcripts and signaling pathways
BackgroundObesity rates in the U.S. continue to increase, with nearly 50% of the population being either obese or morbidly obese. Obesity, along with...
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Effect of blood flow restriction and electrical muscle stimulation on human glycemic response to a glucose challenge
PurposeTo determine whether reduced tissue oxygen availability through blood flow restriction (BFR) alone, or in combination with electrically...
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Changes in aquaporins expression due to acute water restriction in naturally aging mice
Aquaporins (AQPs) are water channels in the cell membrane that regulate osmosis in response to rapid changes in intracellular and extracellular fluid...
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Caloric restriction and metformin selectively improved LKB1-mutated NSCLC tumor response to chemo- and chemo-immunotherapy
BackgroundAbout 10% of NSCLCs are mutated in KRAS and impaired in STK11/LKB1 , a genetic background associated with poor prognosis, caused by an...
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Comparative Characteristics of Sialoglycans Expression Disorders in the Placental Barrier Structures in Preeclampsia and Fetal Growth Restriction
We compared the expression profiles of α2,3- and α2,6-sialoglycans in the glycocalyx of the placental barrier structures in early and late forms of...
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Fetal growth restriction: associated genetic etiology and pregnancy outcomes in a tertiary referral center
BackgroundThe etiology of fetal growth restriction (FGR) is complex and currently, there is a paucity of research about the genetic etiology of fetal...
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Efficacy of progressive versus severe energy restriction on body composition and strength in concurrent trained women
PurposeThis study evaluated the concurrent training (CT) effect in combination with either progressive energy restriction (PER) or severe energy...
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Dietary sulfur amino acid restriction in humans with overweight and obesity: a translational randomized controlled trial
BackgroundDietary sulfur amino acid restriction (SAAR) improves metabolic health in animals. In this study, we investigated the effect of dietary...
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Activation of neurons in the insular cortex and lateral hypothalamus during food anticipatory period caused by food restriction in mice
Mice fed a single meal daily at a fixed time display food anticipatory activity (FAA). It has been reported that the insular cortex (IC) plays an...
