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Higher plasma interleukin − 6 levels are associated with lung cavitation in drug-resistant tuberculosis
BackgroundLung cavitation is associated with heightened TB transmission and poor treatment outcomes. This study aimed to determine the relationship...
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Pulmonary Drug Delivery
This chapter provides an introductory overview on concepts related to drug delivery to the lungs. Physiological barriers to lung delivery are... -
Pulmonary cavitation in patients with thyroid cancer receiving antiangiogenic agents
BackgroundThyroid malignancies are among the most common endocrine cancers worldwide. Owing to the angiogenic nature of these malignancies, tyrosine...
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Acoustic Vortex-Assisted Thrombolysis Treatment in a Pulmonary Embolism Model Using a Miniature Ultrasound Catheter
PurposePulmonary embolism (PE) occurs when a blood clot, usually from the deep veins of the legs, travels through the bloodstream and becomes lodged...
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Detection of serum Aspergillus-specific IgM and IgG antibody levels for the diagnosis of chronic pulmonary aspergillosis developed in patients with tuberculosis
Chronic pulmonary aspergillosis (CPA) is common among individuals with underlying lung diseases. The clinical manifestations of CPA include systemic...
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The roles of neutrophils in non-tuberculous mycobacterial pulmonary disease
Non-tuberculous Mycobacterial Pulmonary Disease (NTM-PD) is an increasingly recognised global health issue. Studies have suggested that neutrophils...
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Risk factors for short-term prognosis of end-stage liver disease complicated by invasive pulmonary aspergillosis
Background and aimPatients with end-stage liver disease (ESLD) are susceptible to invasive pulmonary aspergillosis (IPA). This study aimed to...
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Blood monocyte and dendritic cell profiles among people living with HIV with Mycobacterium tuberculosis co-infection
BackgroundUnderstanding the complex interactions of the immune response mediated by Mycobacterium tuberculosis and HIV co-infection is fundamental...
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Necroptosis-related subtypes are associated with bronchiectasis in pulmonary non-tuberculous mycobacteria-infected patients: a perspective based on transcriptomic analysis
The aim of this study was to explore the potential mechanisms responsible for the different manifestations of bronchiectasis in patients with...
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Protective Performance of Helmets and Goggles in Mitigating Brain Biomechanical Response to Primary Blast Exposure
The current combat helmets are primarily designed to mitigate blunt impacts and ballistic loadings. Their protection against primary blast wave is...
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Role of Bronchoscopy in Diagnostics and Treatment of Tuberculosis
Modern bronchoscopyBronchoscopy plays a crucial role in confirming pulmonary or endobronchial tuberculosisTuberculosisendobronchial (TB), providing a... -
Drug Discovery for Non-tuberculous Mycobacteria: Recent Updates
MycobacteriumMycobacterium is a genusGenus that includes several pathogenic speciesSpecies. SpeciesSpecies causing tuberculosis (TB) and... -
Disseminated nocardiosis and anti-GM-CSF antibodies
Infections that are unusually severe or caused by opportunistic pathogens are a hallmark of primary immunodeficiency (PID). Anti-cytokine...
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Severe necrotizing tracheobronchitis caused by influenza B and methicillin-resistant Staphylococcus aureus co-infection in an immunocompetent patient
Purpose and methodNecrotizing tracheobronchitis is a rare clinical entity presented as a necrotic inflammation involving the mainstem trachea and...
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Therapeutical strategies in cavitary legionnaires’ disease, two cases from the field and a systematic review
BackgroundLegionnaires’ Disease (LD) rarely evolves into pulmonary abscesses. The current systematic review has been designed to explore...
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Long-Term Sequelae of COVID-19 in Experimental Mice
We recently reported acute COVID-19 symptoms, clinical status, weight loss, multi-organ pathological changes, and animal death in a murine hepatitis...
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Tuberculosis
Tuberculosis is one of the major global health concerns associated with a high morbidity and mortality rate. Pulmonary tuberculosis may remain latent... -
Helper T cell bias following tuberculosis chemotherapy identifies opportunities for therapeutic vaccination to prevent relapse
Therapeutic vaccines have promise as adjunctive treatment for tuberculosis (TB) or as preventives against TB relapse. An important development...
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The Pathogenesis and Progression of Sarcoidosis from the Standpoint of Tuberculosis
Tuberculosis (TB) is a systemic necrotizing granulomatous disease caused by Mycobacterium tuberculosisMycobacterium tuberculosis that mainly affects... -
Usefulness of a predictive model to hospitalize patients with low-risk community-acquired pneumonia
IntroductionA high proportion of patients with low-risk community-acquired pneumonia (CAP) (classes I-III of the Pneumonia Severity Index) are...