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Body Mass as a Biomarker and Femoral Fracture
Body mass represents a wide range of components, from atoms to tissues or organs. In clinical practice, body composition is generally assessed at the... -
Body Mass as a Biomarker and Femoral Fracture
Body mass represents a wide range of components, from atoms to tissues or organs. In clinical practice, body composition is generally assessed at the... -
Effect of immunology biomarkers associated with hip fracture and fracture risk in older adults
Osteoporosis is a skeletal disease that can increase the risk of fractures, leading to adverse health and socioeconomic consequences. However,...
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An atlas of genetic determinants of forearm fracture
Osteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive....
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Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
BackgroundAccurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal...
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Quantitative Ultrasound (QUS) in the Management of Osteoporosis and Assessment of Fracture Risk: An Update
Quantitative ultrasound (QUS) presents a low cost and readily available alternative to DXA measurements of bone mineral density (BMD) for... -
Finite Element Analysis of Femoral Strains in Older Adults During Stair Ascent and Descent
PurposeUnderstanding the femur load environment during daily activity is necessary for the understanding of risk of femoral pain, pain related falls,...
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Body Anthropometry and Bone Strength Conjointly Determine the Risk of Hip Fracture in a Sideways Fall
We hypothesize that variations of body anthropometry, conjointly with the bone strength, determine the risk of hip fracture. To test the hypothesis,...
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Osteoporosis Prediction Using Machine-Learned Optical Bone Densitometry Data
Optical bone densitometry (OBD) has been developed for the early detection of osteoporosis. In recent years, machine learning (ML) techniques have...
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Pulse-Echo Measurements of Bone Tissues. Techniques and Clinical Results at the Spine and Femur
The aim of this chapter is to review the available pulse-echo approaches for the quantitative evaluation of bone health status, with a specific... -
Acute spinal cord injury serum biomarkers in human and rat: a sco** systematic review
Study designSco** systematic review.
ObjectivesTo summarize the available experimental clinical and animal studies for the identification of all...
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Osteoporosis
Osteoporosis is a systemic skeletal disease associated with an increased risk of fracture and characterized by reduced bone mass and qualitative... -
Surgical Management of Metastatic Disease to the Lower Extremity
Metastatic skeletal disease of the lower extremity can lead to significant morbidity and quality of life diminishment due to the stresses in the... -
Three-Dimensional Musculoskeletal Model of the Lower Extremity: Integration of Gait Analysis Data with Finite Element Analysis
PurposeThe human lower extremity is an indispensable system for generating walking and movement. This important system may fail due to joint diseases...
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Clinical Devices for Bone Assessment
Although it has been over 30 years since the first recorded use of quantitative ultrasound (QUS) technology to predict bone strength, the field has... -
Current knowledge of bone-derived factor osteocalcin: its role in the management and treatment of diabetes mellitus, osteoporosis, osteopetrosis and inflammatory joint diseases
Osteocalcin (OC) is the most abundant non-collagenous and osteoblast-secreted protein in bone. It consists of two forms such as carboxylated OC (cOC)...
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Severe Calcaneus Injury Probability Curves Due to Under-Body Blast
The lower extremity is the most frequently injured body region to mounted soldiers during underbody blast (UBB) events. UBB events often produce...
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Lower Extremity Impact and Injury Responses of Male and Female PMHS to High-Rate Vertical Loading
Whole-body PMHS (Post Mortem Human Surrogate) testing was conducted on the Accelerative Loading Fixture (ALF), which is designed to generate floor...