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Sex-steroid hormones and risk of postmenopausal estrogen receptor-positive breast cancer: a case–cohort analysis
PurposeSex-steroid hormones are associated with postmenopausal breast cancer but potential confounding from other biological pathways is rarely...
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Trajectories of body mass index in adulthood and risk of subtypes of postmenopausal breast cancer
BackgroundBody fatness is a dynamic exposure throughout life. To provide more insight into the association between body mass index (BMI) and...
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Association of air pollution with postmenopausal breast cancer risk in UK Biobank
BackgroundWe investigated the association of several air pollution measures with postmenopausal breast cancer (BCa) risk.
MethodsThis study included...
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Breast Cancer
Breast cancers are a major cause of mortality in females, on a par with lung and colon cancers. One topic in this chapter are the causes of breast...
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Immunotherapy in Breast Cancer
Breast cancer affects 12% of women worldwide. Although advances in systemic, surgical, and radiation therapy approaches will cure a large proportion...
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Breast Cancer
Breast cancer is currently the most diagnosed cancer in the female population, with a prevalence of 1 in 8 women.
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Mechanisms of Drug Resistance in Breast Cancer
The incidence of breast cancer has increased over the past decades making it the most common cancer in females worldwide. Multidrug resistance (MDR)...
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Introduction to Breast Cancer
Breast cancer is the leading cause of mortality among women worldwide. Being a heterogenous disease it comprises many different subtypes that differ...
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A metabolomic analysis of adiposity measures and pre- and postmenopausal breast cancer risk in the Nurses’ Health Studies
BackgroundAdiposity is consistently positively associated with postmenopausal breast cancer and inversely associated with premenopausal breast cancer...
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Low-dose acetylsalicylic acid reduces local inflammation and tissue perfusion in dense breast tissue in postmenopausal women
PurposeOne major risk factor for breast cancer is high mammographic density. It has been estimated that dense breast tissue contributes to ~ 30% of...
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The impact of PIK3CA mutations and PTEN expression on the effect of neoadjuvant therapy for postmenopausal luminal breast cancer patients
BackgroundThere is pressing needs to find the biomarker in the selection of neoadjuvant therapy in postmenopausal luminal breast cancer patients. We...
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Body size in early life and the risk of postmenopausal breast cancer
BackgroundGreater early life adiposity has been reported to reduce postmenopausal breast cancer risk but it is unclear whether this association...
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Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer
BackgroundObesity and adult weight gain are linked to increased breast cancer risk and poorer clinical outcomes in postmenopausal women, particularly...
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Changes in intestinal microbiota in postmenopausal oestrogen receptor-positive breast cancer patients treated with (neo)adjuvant chemotherapy
This clinical study explored the associations between the intestinal microbiota, chemotherapy toxicity, and treatment response in postmenopausal...
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Long-term effects of aromatase inhibitors on body mass index among postmenopausal breast cancer survivors in Africa: observational cohort study
Purposethis study was conducted to assess the impact of AIs on body mass index and high sensitivity as prognostic predictors to be incorporated into...
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Novel CDK Inhibitors in Breast Cancer
Breast cancer is thought to be the most frequent kind of cancer in women globally. It is crucial to comprehend the biology of this tumor before...
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Breast Cancer Therapy and Control
We discuss breast cancer therapy using drugs in this chapter. Genetic mutations are usually irreversible and they cannot be altered by giving drugs...
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Lifetime changes in body fatness and breast density in postmenopausal women: the FEDRA study
BackgroundHigh mammographic breast density (MBD) is an established risk factor for breast cancer (BC). Body fatness conveys an increased BC risk in...
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Role of Endorphins in Breast Cancer Pathogenesis and Recovery
Understanding the relationship between stress and breast cancer development is essential to preventing and alleviating the cancer. Recent research...
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Molecular Profiling and Personalized Medicine in Drug-Resistant Breast Cancer
The utilization of molecular profiling techniques and personalized medicine approaches in the management of breast cancer is driven by molecular...