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Ovarian tissue cryopreservation and transplantation: a review on reactive oxygen species generation and antioxidant therapy
Cancer is the leading cause of death worldwide. Fortunately, the survival rate of cancer continues to rise, owing to advances in cancer treatments....
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Essential role of PLD2 in hypoxia-induced stemness and therapy resistance in ovarian tumors
BackgroundHypoxia in solid tumors is an important source of chemoresistance that can determine poor patient prognosis. Such chemoresistance relies on...
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Ovarian transposition before radiotherapy in cervical cancer patients: functional outcome and the adequate dose constraint
BackgroundThe data regarding a transposed ovary in intensity-modulated radiotherapy (IMRT) are not sufficient. Here we aim to investigate the...
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Effects of Environment and Lifestyle Factors on Premature Ovarian Failure
Premature ovarian insufficiency (POI) or primary ovarian failure is defined as a cessation of the menstrual cycle in women younger than 40 years old....
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Association between the location of transposed ovary and ovarian dose in patients with cervical cancer treated with postoperative pelvic radiotherapy
Background and purposeHow to protect the ovarian function during radiotherapy is uncertain. The purpose of this study was to explore the association...
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Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
The aim of this systematic review study is to summarize the current knowledge of ovarian tissue transplantation and provide insight on ovarian...
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Analysis of Transcriptome of Drosophila melanogaster Strains with Disrupted Control of gypsy Retrotransposon Transposition
AbstractTo study the causes of impaired control of the activity of mobile genetic elements in the strains with the flamenco phenotype SS ( w , flamenco ...
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Regulation of Uni-Strand and Dual-Strand piRNA Clusters in Germ and Somatic Tissues in Drosophila melanogaster under Control of rhino
AbstractDrosophila melanogaster is a common genetic object for research of RNA interference pathways and regulation of mobile elements. At present,...
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Towards targeting transposable elements for cancer therapy
Transposable elements (TEs) represent almost half of the human genome. Historically deemed ‘junk DNA’, recent technological advancements have...
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Decellularization Methods of Ovary in Tissue Engineering
The ovaries or female gonads are situated in the ovarian fossa of the abdominal cavity. These are paired, almond-shaped organs measuring about 3.5 cm...
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Transposable elements as essential elements in the control of gene expression
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile elements, make up a significant portion of the genomes of...
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The sixth Japanese meeting on biological function and evolution through interactions between hosts and transposable elements
The sixth Japanese meeting on host–transposon interactions, titled “Biological Function and Evolution through Interactions between Hosts and...
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Meeting report: transposable elements at the crossroads of evolution, health and disease 2023
The conference “Transposable Elements at the Crossroads of Evolution, Health and Disease” was hosted by Keystone Symposia in Whistler, British...
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Pan cancer characterization of genes whose expression has been associated with LINE-1 antisense promoter activity
BackgroundLong interspersed nuclear element-1 (LINE-1 or L1) comprises 17% of the human genome. As the only autonomous and active retrotransposons,...
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Use of Drosophila Transgenics to Identify Functions for Symbiont Effectors
Wolbachia, one of the most successful and studied insect symbionts, and Drosophila, one of the most understood model insects, can be exploited as...
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Transposable elements in Drosophila
Drosophila has been studied as a biological model for many years and many discoveries in biology rely on this species. Research on transposable...
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Human Genetics of Semilunar Valve and Aortic Arch Anomalies
Lesions of the semilunar valve and the aortic arch can occur either in isolation or as part of well-described clinical syndromes. The polygenic cause...
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Develo** an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies
BackgroundEarly detection of colorectal neoplasms can reduce the colorectal cancer (CRC) burden by timely intervention for high-risk individuals....
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The composition dynamics of transposable elements in human blastocysts
Transposable elements (TEs) are mobile DNA sequences that can replicate themselves and play significant roles in embryo development and chromosomal...
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A 39 kb structural variant causing Lynch Syndrome detected by optical genome map** and nanopore sequencing
Lynch Syndrome (LS) is a hereditary cancer syndrome caused by pathogenic germline variants in one of the four mismatch repair (MMR) genes MLH1 , MSH2 , MSH6...
