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Fluorescence Recognition of Hydrazine Driven by Neighboring Group Participation
Hydrazine (N 2 H 4 ) has toxic effects on the environment. Although a variety of reactive probes have been used to identify hydrazine, practical...
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Studying the genetics of participation using footprints left on the ascertained genotypes
The trait of participating in a genetic study probably has a genetic component. Identifying this component is difficult as we cannot compare genetic...
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MR Imaging in Ataxias: Consensus Recommendations by the Ataxia Global Initiative Working Group on MRI Biomarkers
With many viable strategies in the therapeutic pipeline, upcoming clinical trials in hereditary and sporadic degenerative ataxias will benefit from...
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Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI)
The gene and cell therapy field saw its first approved treatments in Europe in 2012 and the United States in 2017 and is projected to be at least a...
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Engaging the Community on Colorectal Cancer Screening Education: Focus Group Discussions Among African Americans
Colorectal cancer (CRC) is the third most diagnosed cancer in the USA, and African Americans experience disproportionate CRC diagnosis and mortality....
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Young people’s perspectives of thyroid cancer screening and its harms after the nuclear accident in Fukushima Prefecture: a questionnaire survey indicating opt-out screening strategy of the thyroid examination as an ethical issue
BackgroundOverdiagnosis of thyroid cancer has become a major global medical issue. Ultrasound-based thyroid cancer screening has promoted...
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Bioinformatical View on the Contribution of MAST/IRE-Dependent Phosphorylation in the Tubulin Code
AbstractProtein kinases represent one of the largest eukaryotic enzyme superfamilies. However, only a few can directly phosphorylate tubulin and...
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Genetic Structure and Genetic History of the Sakha (Yakuts) Population
AbstractThis review summarizes molecular genetic studies on the genetic structure and genetic history of the Sakha (Yakuts) population in the context...
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GABAB Inhibition through Feedback Is Involved in the Synchronization of Interictal Spikes in the Cortex
Recent studies have significantly expanded our understanding of the functions of GABAergic interneurons in cortical neural networks. Interneurons of...
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The Role of Transposable Elements in Long-Term Memory Formation
AbstractA number of experimental studies are described that challenge the significance of synaptic plasticity and prove the role of transposable...
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Summer Clinical Oncology Research Experience (SCORE) Program: Engaging Undergraduates from Diverse Backgrounds in Cancer Research
Diversifying the future cancer research workforce requires that students engage in cancer research, persist in paths toward science, technology,...
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Pallidal GABA B receptors: involvement in cortex beta dynamics and thalamic reticular nucleus activity
The external globus pallidus (GP) firing rate synchronizes the basal ganglia-thalamus-cortex network controlling GABAergic output to different...
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Seropositivity for Toxocara spp. in Individuals with Animal Hoarding Disorder in Southern Brazil: An Alarm for Public Health
PurposeAnimal hoarding has been associated with unhealthy human, animal and environmental conditions that predispose such individuals to serious...
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Local Onco-Sphere: Tumor–Secretome Interaction
In a tissue, cells secrete proteins, soluble factors, cytokines, chemokines, and metabolites to build up a reservoir, also known as the secretome. In... -
Effects of experimental ulcerative colitis on myenteric neurons in P2X7-knockout mice
This study aimed to investigate the distal colon myenteric plexus and enteric glial cells (EGCs) in P2X7 receptor-deficient (P2X7−/−) animals after...
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Cognitive Training in Parkinson’s Disease Induces Local, Not Global, Changes in White Matter Microstructure
Previous studies showed that cognitive training can improve cognitive performance in various neurodegenerative diseases but little is known about the...
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Differences between Alzheimer’s disease and mild cognitive impairment using brain networks from magnetic resonance texture analysis
Several studies have aimed at identifying biomarkers in the initial phases of Alzheimer’s disease (AD). Conversely, texture features, such as those...
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Purinergic signaling in tanycytes and its contribution to nutritional sensing
Tanycytes are hypothalamic radial glial-like cells with an important role in the regulation of neuroendocrine axes and energy homeostasis. These...
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The role of Pannexin-1 channels and extracellular ATP in the pathogenesis of the human immunodeficiency virus
Only recently, the role of large ionic channels such as Pannexin-1 channels and Connexin hemichannels has been implicated in several physiological...