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Soft Tissue Infections
Infections of the skin, subcutaneous fat, muscle, and connective tissues include cellulitis, soft tissue abscesses, tenosynovitis, myositis and...
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Temporal trends of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus in Gabon
BackgroundMethicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of mortality due to bacterial antimicrobial resistance....
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Impact of prior antibiotic therapy on severe necrotizing soft-tissue infections in ICU patients: results from a French retrospective and observational study
Necrotizing soft-tissue infection (NSTI) is a life-threatening pathology that often requires management in intensive care unit (ICU). Therapies...
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Necrotizing Soft Tissue Infections Clinical and Pathogenic Aspects
This volume aims to enhance the current understanding of clinical features, treatment and pathogenic aspects in necrotizing soft tissue infections....
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Treatment of Necrotizing Soft Tissue Infections: IVIG
Immunoglobulins are key effector molecules in the humoral immune response. Intravenous polyspecific immunoglobulin (IVIG) is a preparation of...
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Topical Nanotherapeutics for Treating MRSA-Associated Skin and Soft Tissue Infection (SSTIs)
The emergence of methicillin-resistant Staphylococcus aureus (MRSA) imposes a major challenge for the treatment of infectious diseases with existing...
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Treatment of Necrotizing Soft Tissue Infections: Antibiotics
Necrotizing soft tissue infections (NSTIs) are severe, life-threatening infections, and early therapeutic intervention is essential. Prompt...
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Microbiological Etiology of Necrotizing Soft Tissue Infections
Necrotizing soft tissue infections (NSTIs) are severe clinical conditions requiring swift therapeutic intervention, including surgical removal of...
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Necrotizing Soft-Tissue Infections: Clinical Features and Diagnostic Aspects
The term necrotizing soft-tissue infection (NSTI) encompasses a heterogenous group of patients with necrotizing infections, involving any body part....
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Association between adjunct clindamycin and in-hospital mortality in patients with necrotizing soft tissue infection due to group A Streptococcus: a nationwide cohort study
Necrotizing soft tissue infection (NSTI) due to group A Streptococcus (GAS) is a severe life-threatening microbial infection. The administration of...
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Necrotizing Soft Tissue Infections: Case Reports, from the Clinician’s Perspectives
Necrotizing soft tissue infections (NSTI) are rapidly spreading and life-threatening infections of skin and soft tissue. Essentially there are two...
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Pathogenic Mechanisms of Streptococcal Necrotizing Soft Tissue Infections
Necrotizing skin and soft tissue infections (NSTIs) are severe life-threatening and rapidly progressing infections. Beta-hemolytic streptococci,...
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Beta-Hemolytic Streptococci and Necrotizing Soft Tissue Infections
β-hemolytic streptococci are major causes of necrotizing soft tissue infections (NSTIs), Streptococcus pyogenes (group A streptococcus; GAS) in...
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Reduced interleukin-18 secretion by human monocytic cells in response to infections with hyper-virulent Streptococcus pyogenes
BackgroundStreptococcus pyogenes (group A streptococcus, GAS) causes a variety of diseases ranging from mild superficial infections of the throat...
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The INFECT-Project: An International and Multidisciplinary Project on Necrotizing Soft Tissue Infections
This book describes clinical and microbiologic aspects, pathogenesis, and diagnostics, related to the severe and rapidly spreading necrotizing soft...
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Systems and Precision Medicine in Necrotizing Soft Tissue Infections
Necrotizing soft tissue infections (NSTI) are multifactorial and characterized by dysfunctional, time dependent, highly varying hyper- to...
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Systems Biology and Biomarkers in Necrotizing Soft Tissue Infections
In necrotizing soft tissue infection (NSTI) there is a need to identify biomarker sets that can be used for diagnosis and disease management. The...
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Inflammation and Neutrophil Oxidative Burst in a Family with NFKB1 p.R157X LOF and Sterile Necrotizing Fasciitis
Loss-of-function (LOF) mutations in NFKB1 , coding for p105, may cause common variable immunodeficiency due to dysregulation of nuclear factor...
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Systems Genetics Approaches in Mouse Models of Group A Streptococcal Necrotizing Soft-Tissue Infections
Mouse models are invaluable resources for studying the pathogenesis and preclinical evaluation of therapeutics and vaccines against many human...
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The role of Staphylococcus aureus quorum sensing in cutaneous and systemic infections
BackgroundStaphylococcus aureus is a leading cause of human bacterial infections worldwide. It is the most common causative agent of skin and soft...
