Search
Search Results
-
Salivary leucocytes as suitable biomatrix for the comet assay in human biomonitoring studies
Peripheral blood leucocytes (PBL) have been traditionally used to investigate DNA damage by the comet assay in population studies, but validating...
-
Metabolomic profiling of bovine leucocytes transformed by Theileria annulata under BW720c treatment
BackgroundWhen Theileria annulata infects host cells, it undertakes unlimited proliferation as tumor cells. Although the transformed cells will...
-
Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons
The blood–brain barrier (BBB) restricts the systemic delivery of messenger RNAs (mRNAs) into diseased neurons. Although leucocyte-derived...
-
Development and validation of a clinical nomogram to predict prostatic inflammation in men with lower urinary tract symptoms
BackgroundProstatic inflammation is an important etiological component of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS)....
-
Cerebrospinal fluid cytokine levels are associated with macrophage infiltration into tumor tissues of glioma patients
BackgroundDiffuse gliomas are the most common malignant tumors of the central nervous system with poor treatment efficacy. Infiltration of immune...
-
UHPLC–MS and GC–MS phytochemical profiling, amelioration of pain and inflammation with chloroform extract of Funaria hygrometrica Hedw. via modulation of inflammatory biomarkers
People of Pakistan have undisturbed customs for the employment of medicinal plants for healthcare requisites. Chloroform extract of F. hygrometrica ...
-
Distinct Expression Pattern of Epigenetic Machinery Genes in Blood Leucocytes and Brain Cortex of Depressive Patients
In major depressive disorder (MDD), altered gene expression in brain cortex and blood leucocytes may be due to aberrant expression of epigenetic...
-
Immune Cell Trafficking in the Lymphatics, Hyaluronan Biology and Tumour Metastasis
As an integral part of the immune system, the lymphatics enable immune surveillance by shepherding the migration of antigen-laden immune cells to...
-
Pathogen exposure influences immune parameters around weaning in pigs reared in commercial farms
BackgroundMultiple antigenic stimulations are crucial to immune system training during early post-natal life. These stimulations can be either due to...
-
Low efficiency of leucocyte plugging-based drug delivery to cancer in mice
Cells of the immune system were proposed for use as Trojan horse for tumour-specific drug delivery. The efficacy of such cell-based drug delivery...
-
Isolation and Immunophenoty** of Leukocytes from the Human Maternal-Fetal Interface
During human pregnancy, leukocytes that infiltrate the maternal-fetal interface play a major role in establishing a delicate balance between immune...
-
The Discovery of the Major Histocompatibility Complex (MHC): The H-2 in Mice and the HLA in Man
In this chapter I describe how the major histocompatibility system, the H-2 system, was discovered in mice by Peter Gorer in 1935 in London. This...
-
Leukapheresis increases circulating tumour cell yield in non-small cell lung cancer, counts related to tumour response and survival
BackgroundCirculating tumour cells (CTCs) can be used to monitor cancer longitudinally, but their use in non-small cell lung cancer (NSCLC) is...
-
Evaluation of Leukocyte Chemotaxis Induced by Human Fetal Membranes in an In Vitro Model
Leukocyte infiltration into the maternal-fetal interface is a consequence of the robust inflammation in the gestational tissues during term labor and...
-
Exo-erythrocytic development of Plasmodium matutinum (lineage pLINN1) in a naturally infected roadkill fieldfare Turdus pilaris
BackgroundSpecies of Plasmodium (Haemosporida, Plasmodiidae) are remarkably diverse haemoparasites. Information on genetic diversity of avian...
-
Antioedematogenic and anti-inflammatory actions of Phragmanthera incana (Schum) Balle leaf in carrageenan-induced inflammation models in rats
Phragmanthera incana (Schum) is a specie of mistletoe that has been mentioned in Nigeria ethnomedicine to be used in the treatment of inflammatory...
-
On the survival of 48 h Plasmodium vivax Aotus monkey-derived ex vivo cultures: the role of leucocytes filtration and chemically defined lipid concentrate media supplementation
BackgroundFiltration of leukocytes (WBCs) is a standard practice of malaria ex vivo cultures. To date, few studies have considered the effect of...
-
Memory B Cells Predict Relapse in Rituximab-Treated Myasthenia Gravis
Myasthenia gravis can be efficiently treated with rituximab but there is no consensus regarding administration and dose schedules in this indication....
-
Immunodeficiency Diseases
Immunodeficiency disorders are conditions where the defence mechanism of the body is impaired. They show enhanced susceptibility to infection with...
-
The Diagnostic and Prognostic Value of Synovial Fluid Analysis in Joint Diseases
Liquid biopsy is an emergent test method for the diagnosis and prognosis in the clinic. Joint fluid, also known as synovial fluid, contains a variety...