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Spatial Cluster Change of Schistosoma japonicum Transmission Foci in Indonesia During the Schistosomiasis Elimination Program
PurposeThe Government of Indonesia committed to eliminating schistosomiasis by 2025. Collaboratively snail control became one of the crucial...
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Diversity of trematode cercariae among naturally infected lymnaeid snails from Phayao, Thailand
Lymnaeids are aquatic snails playing an important role in the transmission of many parasitic trematode species of veterinary and medical importance....
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Evaluation of the TLR3 involvement during Schistosoma japonicum-induced pathology
BackgroundDespite the functions of TLRs in the parasitic infections have been extensively reported, few studies have addressed the role of TLR3 in...
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Schistosoma japonicum EKLF/KLF1 is a potential immune target to tackle schistosomiasis
BackgroundInterruption of parasite reproduction by targeting migrating schistosomula is a promising strategy for managing schistosomiasis. Hepatic...
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Galectin-receptor interaction: a key player in liver fibrosis induced by Schistosoma japonicum infection
BackgroundSchistosoma japonicum eggs lodge in the liver and induce a fibrotic granulomatous immune response in the liver of host. Galectin 3 (Gal-3)...
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An improved medium for in vitro studies of female reproduction and oviposition in Schistosoma japonicum
BackgroundSchistosomiasis is a disease primarily caused by eggs laid by pathogens called schistosomes. Among the schistosome species infecting...
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A prognostic model for Schistosoma japonicum infection-associated liver hepatocellular carcinoma: strengthening the connection through initial biological experiments
BackgroundNumerous studies have shown that Schistosoma japonicum infection correlates with an increased risk of liver hepatocellular carcinoma...
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Characterizing genetic variation on the Z chromosome in Schistosoma japonicum reveals host-parasite co-evolution
BackgroundSchistosomiasis is a neglected tropical disease that afflicts millions of people worldwide; it is caused by Schistosoma, the only dioecious...
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Type I/II Immune Balance Contributes to the Protective Effect of AIF-1 on Hepatic Immunopathology Induced by Schistosoma japonicum in a Transgenic Mouse Model
Schistosomiasis is the second most debilitating neglected tropical disease in the world. Liver egg granuloma and fibrosis are the main damage of...
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MicroRNA-29a-3p prevents Schistosoma japonicum-induced liver fibrosis by targeting Roundabout homolog 1 in hepatic stellate cells
BackgroundSchistosomiasis is a serious but neglected parasitic disease in humans that may lead to liver fibrosis and death. Activated hepatic...
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Construction and characterization of microsatellite markers for the Schistosoma japonicum isolate from a hilly area of China based on whole genome sequencing
Schistosoma japonicum had once caused the greatest disease burden in China and has still been transmitted in some hilly areas, for example, in Shitai...
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Schistosoma japonicum Associated Colorectal Cancer and Its Management
BackgroundAn association between Schistosoma japonicum and colorectal cancer in humans has been known since a long time; however, this association...
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Exploring the immune interactions between Oncomelania hupensis and Schistosoma japonicum, with a cross-comparison of immunological research progress in other intermediate host snails
Schistosomiasis, the second largest parasitic disease in the world after malaria, poses a significant threat to human health and causes public health...
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IL-37 alleviates liver granuloma caused by Schistosoma japonicum infection by inducing alternative macrophage activation
BackgroundHepatic macrophages regulate liver granuloma formation and fibrosis caused by infection with Schistosoma japonicum , with the manner of...
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Circulating cell-free DNA as a biomarker for diagnosis of Schistosomiasis japonica
BackgroundSchistosomiasis, a neglected tropical disease, remains an important public health problem. Although there are various methods for...
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Deficiency of PKCλ/ι alleviates the liver pathologic impairment of Schistosoma japonicum infection by thwarting Th2 response
BackgroundThe activation of immune response driven by the eggs of Schistosoma japonicum and the subsequent secretions is the culprit behind...
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Morphological and molecular identification of trematode cercariae related with humans and animal health in freshwater snails from a lake and a dam in Myanmar
Freshwater snails play an essential role in the transmission of trematode parasitic flatworms that can infect wild and domestic animals, as well as...
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miR-181a regulates the host immune response against Schistosoma japonicum infection through the TLR4 receptor pathway
BackgroundSchistosomiasis japonica is a serious zoonotic parasitic disease. Preliminary studies have shown that the expression of microRNA-181a...
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A new ferritin SjFer0 affecting the growth and development of Schistosoma japonicum
BackgroundSchistosomiasis, an acute and chronic parasitic disease, causes substantial morbidity and mortality in tropical and subtropical regions of...
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Involvement of the fatty acid-binding protein in the growth of Schistosoma japonicum schistosomula
This study aimed to explore the effect and mechanism underlying the role of the Schistosoma japonicum antigen of fatty acid-binding protein ( Sj FABP)...