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1. Exosomal circZNF800 Derived from Glioma Stem-like Cells Regulates Glioblastoma Tumorigenicity via the PIEZO1/Akt Axis

   Exosomes play a crucial role in regulating crosstalk between tumor and tumor stem-like cells through their cargo molecules. Circular RNAs (circRNAs)...

   Ning Zhang, Pengfei Wu, ... Shanshan Hu in Molecular Neurobiology

   Article Open access 07 February 2024
   

2. GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin

   It has been widely reported that glioma stem-like cells (GSCs) serve a crucial role in the malignant progression of glioma. In particular, recent...

   Haiyang Wang, Ding Wang, ... Quan Du in Cancer Gene Therapy

   Article 02 December 2022
   

3. DNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells

   Background

   High-grade gliomas are primary brain cancers with unacceptably low and persistent survival rates of 10–16 months for WHO grade 4 gliomas...

   Aurelie Vanderlinden, Callum G. Jones, ... Spencer J. Collis in British Journal of Cancer

   Article Open access 30 September 2023
   

4. Comprehensive profiling of stem-like features in pediatric glioma cell cultures and their relation to the subventricular zone

   Pediatric high-grade gliomas (pHGG) are brain tumors occurring in children and adolescents associated with a dismal prognosis despite existing...

   Marc-Antoine Da-Veiga, Natacha Coppieters, ... Caroline Piette in Acta Neuropathologica Communications

   Article Open access 16 June 2023
   

5. Studying Synaptic Integration of Glioma Cells into Neural Circuits

   Nervous system activity regulates homeostasis, development, and plasticity of the brain. Certain glial cell populations regulate neuronal activity by...

   Kiarash Shamardani, Kathryn R. Taylor, ... Michelle Monje in New Technologies for Glutamate Interaction

   Protocol 2024
   

6. Mesenchymal stem cells as therapeutic vehicles for glioma

   Glioma is a disease with a poor prognosis despite the availability of multimodality treatments, and the development of novel therapies is urgently...

   Tomoya Oishi, Shinichiro Koizumi, Kazuhiko Kurozumi in Cancer Gene Therapy

   Article 23 April 2024
   

7. Glioma

   Most adult neurons have exited the cell cycle. Therefore, almost all primary brain cancers in the adult body are related to glial cells. There exists...

   Wolfgang Walz in The Gliocentric Brain

   Chapter 2023
   

8. The strategies to cure cancer patients by eradicating cancer stem-like cells

   Cancer stem-like cells (CSCs), a subpopulation of cancer cells, possess remarkable capability in proliferation, self-renewal, and differentiation....

   Yansui Mai, Jiyan Su, ... Liwu Fu in Molecular Cancer

   Article Open access 18 October 2023
   

9. ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia

   Background

   In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However,...

   Tao-Yan Lin, Jun-Shuang Jia, ... Yan Sun in Journal of Experimental & Clinical Cancer Research

   Article Open access 29 February 2024
   

10. Malignant Glioma

    This chapter provides a comprehensive overview of malignant gliomasMalignant glioma, the most common primary brain tumorPrimary brain tumor in...

    Linda M. Wang, Zachary K. Englander, ... Jeffrey N. Bruce in Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2

    Chapter 2023
    

11. A Three-Dimensional Organoid Culture System to Model Invasive Patterns of Patient-Derived Glioma Stem Cells

    Glioblastoma multiformes (GBMs) are recurring brain tumors containing self-renewing glioma stem cells (GSCs), which contribute to tumor initiation...

    Aruljothi Mariappan, Theda Knauth, ... Jay Gopalakrishnan in Brain Organoid Research

    Protocol 2023
    

12. Glioblastoma CD105⁺ cells define a SOX2⁻ cancer stem cell-like subpopulation in the pre-invasive niche

    Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular...

    Jiaxin Li, Fredrik Ek, ... Johan Bengzon in Acta Neuropathologica Communications

    Article Open access 29 August 2022
    

13. Benign Glioma

    BenignBenign gliomaGliomas broadly refers to a heterogeneousHeterogeneous group of slow-growing glial tumors with low proliferative rates and a more...

    Peter B. Wu, Anna C. Filley, ... Jeffrey N. Bruce in Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2

    Chapter 2023
    

14. Vimentin promotes glioma progression and maintains glioma cell resistance to oxidative phosphorylation inhibition

    Purpose

    Glioma has been demonstrated as one of the most malignant intracranial tumors and currently there is no effective treatment. Based on our...

    Yu’e Liu, Shu Zhao, ... Kaijun Zhao in Cellular Oncology

    Article 30 August 2023
    

15. The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis

    Glioma is the most common type of solid tumour affecting the central nervous system, and the survival rate of patients with glioma is low. However,...

    Faming Wang, Le Zhang, ... Liudi Yuan in Molecular Neurobiology

    Article 10 March 2021
    

16. Glioma Cells Expressing High Levels of ALDH5A1 Exhibit Enhanced Migration Transcriptional Signature in Patient Tumors

    Accumulating data shows that altered metabolic activity contributes to glioma development. Recently, modulation of SSADH (succinic semialdehyde...

    Christina Piperi, Mirca S. Saurty-Seerunghen, ... Penelope Korkolopoulou in Neurotherapeutics

    Article 28 March 2023
    

17. Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells

    For all living organisms, the adaptation to outside environments is an essential determinant to survive natural and artificial selections and to...

    Kouichi Tabu, Tetsuya Taga in Inflammation and Regeneration

    Article Open access 30 November 2022
    

18. miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM)

    Background

    Gliomas account for about 80% of all malignant brain and other central nervous system (CNS) tumors. Temozolomide (TMZ) resistance...

    Zongze He, Meixiong Cheng, ... Jian Tang in Journal of Translational Medicine

    Article Open access 01 October 2022
    

19. Role of the Shh Signaling Pathway in the Most Common Brain Tumor “Glioma” role in Glioma Growth

    The sonic hedgehog (Shh) signaling pathway is not only critical for brain development but also contributes to glioma growth. It was reported that...

    Mehdi Hayat Shahi in Role of Signaling Pathways in Brain Tumorigenesis

    Chapter 2023
    

20. A prognostic neural epigenetic signature in high-grade glioma

    Neural–tumor interactions drive glioma growth as evidenced in preclinical models, but clinical validation is limited. We present an epigenetically...

    Richard Drexler, Robin Khatri, ... Franz L. Ricklefs in Nature Medicine

    Article Open access 17 May 2024