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Reverse Genetics of Dengue Virus
Dengue virus (DENV) is one of the most important and widespread arthropod-borne viruses, causing millions of infections over the years. Considering... -
Dengue Virus Methods and Protocols
This detailed volume explores various aspects of the dengue virus and its four serotypes (DENV1-4). Beginning with a section on protocols to produce... -
Dengue virus pathogenesis and host molecular machineries
Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly...
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Severe disease during both primary and secondary dengue virus infections in pediatric populations
Dengue is a global epidemic causing over 100 million cases annually. The clinical symptoms range from mild fever to severe hemorrhage and shock,...
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Prediction of B cell epitopes in envelope protein of dengue virus using immunoinformatics approach
In India, recent outbreaks of dengue virus infection have become a major public health issue. As a result, a vaccine to prevent the infection or a...
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Role of angiotensin II in cellular entry and replication of dengue virus
Previous studies have demonstrated the relevance of several soluble molecules in the pathogenesis of dengue. In this regard, a possible role for...
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Natural vertical transmission of dengue virus in Latin America and the Caribbean: highlighting its detection limitations and potential significance
Dengue continues to be a major public health concern in Latin America and the Caribbean with many countries in the region having experienced drastic...
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Attenuated Dengue virus PV001-DV induces oncolytic tumor cell death and potent immune responses
BackgroundViral therapies developed for cancer treatment have classically prioritized direct oncolytic effects over their immune activating...
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Rational design of multi-epitope-based vaccine by exploring all dengue virus serotypes proteome: an immunoinformatic approach
Millions of people’s lives are being devastated by dengue virus (DENV), a severe tropical and subtropical illness spread by mosquitoes and other...
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Increasing prevalence of malaria and acute dengue virus coinfection in Africa: a meta-analysis and meta-regression of cross-sectional studies
BackgroundMalaria and dengue fever are the leading causes of acute, undifferentiated febrile illness. In Africa, misdiagnosis of dengue fever as...
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Molecular evolution of dengue virus: a Bayesian approach using 1581 whole-genome sequences from January 1944 to July 2022
Dengue is a viral disease transmitted by mosquitoes that has spread rapidly across all continents in recent years. There are four distinct but...
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Dengue along the Silk Road
Dengue is a mosquito-borne viral disease that has rapidly spread in all regions of the world in recent years, including the BRI countries. Dengue... -
Virus Propagation and Plaque Assay for Dengue Virus
This chapter describes the methods of propagation and titration for DENV-1 to -4, which are required for most of the experiments using live viruses.... -
Obtention of Dengue Virus Membrane Proteins and Role for Virus Assembly
The four serotypes of dengue virus (DENV), belonging to the genus Flavivirus in the family Flaviviridae, are the leading cause of arboviral diseases... -
Expression of dengue virus and Zika virus NS2B-NS3pro constructs alter cellular fatty acids, but co-expression with a Zika virus virus-like particle is detrimental to virus-like particle expression
ObjectiveStudies have shown that Flavivirus infection remodels the host cell to favour viral replication. In particular, the host cell lipid profile...
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Catastrophic tumefactive acute disseminated encephalomyelitis in patient with dengue virus: a case report
Tumefactive demyelinating lesions (TDL) are a rare occurrence among inflammatory demyelinating diseases of the central nervous system, distinguished...
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Molecular surveillance for dengue serotypes among the population living in Moyen-Ogooué province, Gabon; evidence of the presence of dengue serotype 1
BackgroundDespite dengue virus (DENV) outbreak in Gabon a decade ago, less is known on the potential circulation of DENV serotypes in the country....
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Genoty** of dengue virus from infected tissue samples embedded in paraffin
Dengue has become one of the vector-borne diseases that affect humans worldwide. In Latin American countries, Colombia is historically one of the...
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Inhibition of dengue virus infection by trifluoperazine
Dengue virus (DENV), a member of the genus Flavivirus , family Flaviviridae , is the most widespread viral pathogen transmitted to humans by...
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Genetic characterization of dengue virus from patients presenting multi-serotypic infections in the Northern West Bengal, India
Northern West Bengal, popularly known as North Bengal, is a dengue-endemic area, which has been severely affected by Dengue in the past few years...