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Immune Response
The specific reactivity induced by an antigenic stimulus in a host is known as an immune response. The immune system is developed in a host primarily...
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Comparative evaluation of cell-mediated immune response in calves immunized with live-attenuated and killed Theileria annulata vaccines
Tropical theileriosis is a tick-borne disease caused by the protozoan Theileria annulata and transmitted by numerous species of Ixodid ticks of the...
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The Immune Response
The process of viral infection having been briefly described, it is important to present the mechanisms involved in the immune response of the...
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Chaperone- and PTM-mediated activation of IRF1 tames radiation-induced cell death and the inflammatory response
The key role of structural cells in immune modulation has been revealed with the advent of single-cell multiomics, but the underlying mechanism...
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TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma
Glioblastoma (GB) IDH-wildtype is the most malignant primary brain tumor. It is particularly resistant to current immunotherapies. Translocator...
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Single-cell characterisation of tissue homing CD4 + and CD8 + T cell clones in immune-mediated refractory arthritis
BackgroundImmune-mediated arthritis is a group of autoinflammatory diseases, where the patient’s own immune system attacks and destroys synovial...
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Aberrant R-loop–mediated immune evasion, cellular communication, and metabolic reprogramming affect cancer progression: a single-cell analysis
Dysregulation of R-loop homeostasis is closely related to various human diseases, including cancer. However, the causality of aberrant R-loops in...
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Echinococcosis Immune Response, Immunopathogenesis and Immune Evasion from the Human Host
Echinococcosis is a worldwide parasitic disease with great harm and complicated immune mechanisms. Immunoprophylaxis is an ideal way to prevent...
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Immune Response to Staphylococcus aureus
Although Staphylococcus aureus is not a high virulent pathogen in healthy persons, this bacterium often persists in various tissues and mucosa and...
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Molluscum Contagiosum Virus: Biology and Immune Response
Molluscum contagiosumMolluscum contagiosum virus is a poxvirus belonging to the Poxviridae family, which includes Orthopoxvirus, Parapoxvirus,...
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Evading the Antitumour Immune Response
The mutations that cause (or accompany) malignancy result in tumour cells being detected as “non-self” by the immune system and may evoke an...
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RNA Metabolism Governs Immune Function and Response
Inflammation is a complex process that protects our body from various insults such as infection, injury, and stress. Proper inflammation is...
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Targeting cGAS/STING signaling-mediated myeloid immune cell dysfunction in TIME
Myeloid immune cells (MICs) are potent innate immune cells serving as first responders to invading pathogens and internal changes to cellular...
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FAS-mediated circRNA-miRNA-mRNA Crosstalk Network Regulates Immune Cell Infiltration in Cerebral Infarction
New data are accumulating on the involvement of interaction among circular RNAs (circRNAs), microRNAs (miRNAs/miRs), and messenger RNAs (mRNAs) in...
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Immune Checkpoint Blockade Response Biomarkers
Cancer immunotherapy based on immune checkpoint blockade (ICB) has demonstrated durable clinical benefit in patients with immunogenic tumors,...
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Mrgprb2-mediated mast cell activation exacerbates Modic changes by regulating immune niches
Modic changes are radiographic features associated with microfracture, low-virulence organism infection and chronic inflammation with inflammatory...
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Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in Cancer
Antibody-dependet cell mediated cytotoxicity is a well known strategy to kill dangerous cells. Some antibody have the potential to bind IgG Fc...
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The Use of Apheresis in Personalized Cell-Mediated Treatment of Prostate Cancer
Beside a supportive therapy of deficient blood component(s) by transfusions, hemotherapy involves the use of apheresis procedures due to plasma or...
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Immune cell-mediated features of non-alcoholic steatohepatitis
Non-alcoholic fatty liver disease (NAFLD) includes a range of hepatic manifestations, starting with liver steatosis and potentially evolving towards...
