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Increased frequency of JC-polyomavirus detection in rheumatoid arthritis patients treated with multiple biologics
Progressive multifocal leukoencephalopathy (PML) represents a rare but potentially fatal reactivation of JC-polyomavirus (JCPyV) recently also...
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Inhibition of human diffuse large B-cell lymphoma growth by JC polyomavirus-like particles delivering a suicide gene
BackgroundDiffuse large B-cell lymphoma (DLBCL) is one of the most common types of aggressive B-cell non-Hodgkin lymphoma. About one-third of...
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Human-, Ovine-, and Bovine-Specific Viral Source Tracking Tools to Discriminate Between the Major Fecal Sources in Agricultural Waters
This study evaluated the sources of fecal contamination in different river catchments, using a combination of microbial source tracking tools, for...
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Human polyomavirus type six in respiratory samples from hospitalized children with respiratory tract infections in Bei**g, China
BackgroundHPyV6 is a novel human polyomavirus (HPyV), and neither its natural history nor its prevalence in human disease is well known. Therefore,...
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Antibodies reacting with JCPyV_VP2 _167-15mer as a novel serological marker for JC polyomavirus infection
BackgroundJC polyomavirus (JCPyV) is a widespread human polyomavirus that usually resides latently in its host, but can be reactivated under...
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A taxonomy update for the family Polyomaviridae
Many distinct polyomaviruses infecting a variety of vertebrate hosts have recently been discovered, and their complete genome sequence could often be...
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Viral miRNAs in plasma and urine divulge JC polyomavirus infection
BackgroundJC polyomavirus (JCPyV) is a widespread human polyomavirus that usually resides latently in its host, but can be reactivated under...
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Detection of human JCPyV and BKPyV in diffuse large B-cell lymphoma of the GI tract
Previous studies have demonstrated that infection with human polyomavirus, such as JCPyV and BKPyV, might be associated with various human tumors....
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JC polyomavirus attachment, entry, and trafficking: unlocking the keys to a fatal infection
The human JC polyomavirus (JCPyV) causes a lifelong persistent infection in the reno-urinary tract in the majority of the adult population worldwide....
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First Detection of Human Papillomaviruses and Human Polyomaviruses in River Waters in Italy
Waterborne exposure to human viruses is possible through contact with contaminated water environments and can result in infections associated with a...
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Polyomavirus interaction with the DNA damage response
Viruses are obligate intracellular parasites that subvert cellular metabolism and pathways to mediate their own replication—normally at the expense...
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UVC Inactivation of dsDNA and ssRNA Viruses in Water: UV Fluences and a qPCR-Based Approach to Evaluate Decay on Viral Infectivity
Disinfection by low-pressure monochromatic ultraviolet (UVC) radiation (253.7 nm) became an important technique to sanitize drinking water and also...
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Circulating human microRNAs are not linked to JC polyomavirus serology or urinary viral load in healthy subjects
BackgroundJC polyomavirus (JCPyV) is a widespread human polyomavirus that usually resides latently in its host. It can be reactivated under...
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Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication
BackgroundThe human polyomavirus BK expresses a 66 amino-acid peptide referred to as agnoprotein. Though mutants lacking agnoprotein are severely...
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Merkel cell polyomavirus infection in childhood: current advances and perspectives
Merkel cell polyomavirus (MCPyV) is a newly discovered human small, non-enveloped, double-stranded DNA virus, which was classified into the Polyomaviridae...
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Detection of novel polyomaviruses in fruit bats in Indonesia
Bats are an important natural reservoir for a variety of viral pathogens, including polyomaviruses (PyVs). The aims of this study were: (i) to...
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Molecular Biology of JC Virus and the Human Demyelinating Disease, Progressive Multifocal Leukoencephalopathy
JC virus (JCV) is a human neurotropic polyomavirus that causes the fatal demyelinating disease of the central nervous system known as progressive...