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Liquid Biopsy in Bladder Cancer
Fluid biopsy based on circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), exosome, and circulating RNA in blood and body fluids has gained...
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MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage
Non-traumatic intracerebral hemorrhage (ICH) is the most common type of hemorrhagic stroke, most often occurring between the ages of 45 and 60....
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Mobile MicroRNAs: Potential for MicroRNA Biogenesis
As shown in Chap. 2 , the short interfering RNA (siRNA) system was thought to be the same as the microRNA (miRNA)...
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Long non-coding RNA Gm11974 aggravates oxygen–glucose deprivation-induced injury via miR-122-5p/SEMA3A axis in ischaemic stroke
Long non-coding RNAs (lncRNAs) play important roles in ischaemic stroke. This study aimed to investigate the role and potential mechanism of lncRNA...
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Quantum MiRNA Code
The C. elegans’s lin-4 discovery in 1993 to date are still limited to C. elegans-specific RNA interference. The function of microRNA (miRNA) is based...
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Targeting microRNAs as a promising anti-cancer therapeutic strategy against traffic-related air pollution-mediated lung cancer
Air pollutants are increasingly emitted into the atmosphere because of the high dependency of humans on fossil-derived fuels. Wind speed and...
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Current Insights into Signature MicroRNA Networks and Signal Transduction in Osteosarcoma
Purpose of ReviewOsteosarcoma is one of the most common types of primary bone tumors that mainly occurs in children and adolescents. It is...
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Plasma MicroRNA (miRNA)s as Novel Markers of Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive fat build-up in the liver without any other evident causes of chronic liver...
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Expression profiling of exosomal miRNAs derived from different stages of infection in mice infected with Echinococcus granulosus protoscoleces using high-throughput sequencing
Echinococcosis is a worldwide zoonosis. The mechanism of the establishment, growth, and persistence of parasites in the host has not been fully...
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Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are not translated into proteins. Since their discovery,...
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Plasma MicroRNA (miRNA)s as Novel Markers of Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive fat build-up in the liver without any other evident causes of chronic liver...
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MicroRNAs as regulators of immune checkpoints in cancer immunotherapy: targeting PD-1/PD-L1 and CTLA-4 pathways
Immunotherapy has revolutionized cancer treatment by harnessing the power of the immune system to eliminate tumors. Immune checkpoint inhibitors...
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MicroRNA as a Versatile Regulator of Wnt the Signaling Pathway in Colorectal Cancer
Colorectal cancer (CRC) is one of the leading causes of cancer-related death that accounted for about one million deaths in 2018 globally. CRC...
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The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis
BackgroundMicroRNA-155 has been discussed as a biomarker in cancer diagnosis and prognosis. Although relevant studies have been published, the role...
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Communication in miRNAs Between Inflammation and Cancer
Inflammatory and immune responses are controlled by microRNAs (miRNAs), and cancer is also regulated by miRNAs. Computing analysis and evidence from...
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Oxidative Stress Modulation with MicroRNAs in Cancers
Cellular stress responses are very dynamic and enable cells to successfully resist various stresses that are essential to optimal cell homeostasis....
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SARS-CoV-2 Mutations Lead to a Decrease in the Number of Tissue-Specific MicroRNA-Binding Regions in the Lung
RNA interference in vertebrates acts as an antiviral mechanism only in undifferentiated embryonic stem cells and is mediated by microRNAs. In somatic...
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Mouse as a Preclinical Model for Studying Small Noncoding RNAs Involved in Colorectal Cancer
Colorectal cancer (CRC) is the third most diagnosed cancer and occupies the second position in death among other cancer deaths in both sexes due to...
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MicroRNA-98: the multifaceted regulator in human cancer progression and therapy
MicroRNA-98 ( miR-98 ) stands as an important molecule in the intricate landscape of oncology. As a subset of microRNAs, these small non-coding RNAs...
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MicroRNAs and the Mediterranean diet: a nutri-omics perspective for lung cancer
Lung cancer is the deadliest cancer type worldwide with ~ 1.8 million deaths per-year. Smoking accounts for ~ 85% of all cases, with a described...
