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Article
Open AccessDefining a core configuration for human centromeres during mitosis
The centromere components cohesin, CENP-A, and centromeric DNA are essential for biorientation of sister chromatids on the mitotic spindle and accurate sister chromatid segregation. Insight into the 3D organiz...
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Protocol
Superresolution Microscopy for Visualization of Physical Contacts Between Chromosomes at Nanoscale Resolution
This protocol describes the fluorescence in situ hybridization (FISH) of DNA probes on mitotic chromosome spreads optimized for two super-resolution microscopy approaches—structured illumination microscopy (SI...
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Article
Author Correction: Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion
In the initial published version of this article, there was an inadvertent omission from the Acknowledgements that this work was supported by Stowers Institute for Medical Research (SIMR-1004) and NIH National...
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Article
Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion
Transplantation of hematopoietic stem cells (HSCs) from human umbilical cord blood (hUCB) holds great promise for treating a broad spectrum of hematological disorders including cancer. However, the limited num...
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Article
Combined expansion microscopy with structured illumination microscopy for analyzing protein complexes
Biologists have long been fascinated with the organization and function of intricate protein complexes. Therefore, techniques for precisely imaging protein complexes and the location of proteins within these c...
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Article
Latency represents sound frequency in mouse IC
Frequency is one of the fundamental parameters of sound. The frequency of an acoustic stimulus can be represented by a neural response such as spike rate, and/or first spike latency (FSL) of a given neuron. Th...