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    Article

    Cutaneous toxicities of mitogen-activated protein kinase inhibitors in children and young adults with neurofibromatosis-1

    Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder which commonly causes neoplasms leading to disfigurement or dysfunction. Mitogen-activated protein kinase inhibitors (MEKi) are generally well-t...

    Brianna C. Peacock, Sanjna Tripathy, Hannah L. Hanania in Journal of Neuro-Oncology (2024)

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    Pediatric high-grade glioma: aberrant epigenetics and kinase signaling define emerging therapeutic opportunities

    Supratentorial pediatric high-grade gliomas (pHGGs) are aggressive malignancies that lack effective treatment options. Deep genomic sequencing by multiple groups has revealed that the primary alterations uniqu...

    Yusha Sun, Cavan P. Bailey, Zsila Sadighi, Wafik Zaky in Journal of Neuro-Oncology (2020)

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    Evaluating pediatric spinal low-grade gliomas: a 30-year retrospective analysis

    Most pediatric spinal tumors are low-grade gliomas (LGGs). Characterization of these tumors has been difficult given their heterogeneity and rare incidence. The objective was to characterize such tumors diagno...

    Steven S. Carey, Zsila Sadighi, Shengjie Wu, Jason Chiang in Journal of Neuro-Oncology (2019)