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Article
Open AccessEntrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial
Although comprehensive biomarker testing is recommended for all patients with advanced/metastatic non-small cell lung cancer (NSCLC) before initiation of first-line treatment, tissue availability can limit tes...
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Article
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma
Minimally invasive approaches to detect residual disease after surgery are needed to identify patients with cancer who are at risk for metastatic relapse. Circulating tumour DNA (ctDNA) holds promise as a biom...
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Article
Open AccessMolecular determinants of response to PD-L1 blockade across tumor types
Immune checkpoint inhibitors targeting the PD-1/PD-L1 axis lead to durable clinical responses in subsets of cancer patients across multiple indications, including non-small cell lung cancer (NSCLC), urothelial...