5 Result(s)
within
Zilong Wen
Life Sciences, general
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Article
Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-α-inducible genes
Brahma-related gene 1 (BRG1 ) is a key component of the ATP-dependent chromatin-remodelling SWI2–SNF2 complex and has been implicated in regulating gene expression, cell-cycle control and tumorigenesis. Here we r...
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Article
Open AccessRegulation of gene expression by FSP27 in white and brown adipose tissue
Brown and white adipose tissues (BAT and WAT) play critical roles in controlling energy homeostasis and in the development of obesity and diabetes. The mouse Fat-Specific protein 27 (FSP27), a member of the ce...
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Article
Open AccessThe spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into all blood cell lineages. Yet, the mechanistic basis for HSC development remains lar...
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Article
Slc20a1b is essential for hematopoietic stem/progenitor cell expansion in zebrafish
Hematopoietic stem and progenitor cells (HSPCs) are able to self-renew and can give rise to all blood lineages throughout their lifetime, yet the mechanisms regulating HSPC development have yet to be discovere...
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Article
Open AccessTumor-associated macrophages promote cholangiocarcinoma progression via exosomal Circ_0020256
This study investigated the exosomal circular RNAs (CircRNAs) produced by tumor-associated macrophages and delivered into the microenvironment of cholangiocarcinoma cells in order to use them as molecular targ...
