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Article
Open AccessMacrophages in tissue repair and regeneration: insights from zebrafish
Macrophages play crucial and versatile roles in regulating tissue repair and regeneration upon injury. However, due to their complex compositional heterogeneity and functional plasticity, deciphering the natur...
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Article
Open AccessSulindac selectively induces autophagic apoptosis of GABAergic neurons and alters motor behaviour in zebrafish
Nonsteroidal anti-inflammatory drugs compose one of the most widely used classes of medications, but the risks for early development remain controversial, especially in the nervous system. Here, we utilized ze...
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Chapter
Learning from Zebrafish Hematopoiesis
Hematopoiesis is a complex process that tightly regulates the generation, proliferation, differentiation, and maintenance of hematopoietic cells. Disruptions in hematopoiesis can lead to various diseases affec...
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Article
Open AccessTumor-associated macrophages promote cholangiocarcinoma progression via exosomal Circ_0020256
This study investigated the exosomal circular RNAs (CircRNAs) produced by tumor-associated macrophages and delivered into the microenvironment of cholangiocarcinoma cells in order to use them as molecular targ...
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Article
Slc20a1b is essential for hematopoietic stem/progenitor cell expansion in zebrafish
Hematopoietic stem and progenitor cells (HSPCs) are able to self-renew and can give rise to all blood lineages throughout their lifetime, yet the mechanisms regulating HSPC development have yet to be discovere...
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Article
Open AccessThe spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into all blood cell lineages. Yet, the mechanistic basis for HSC development remains lar...
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Article
Open AccessRole of AP-2α and MAPK7 in the regulation of autocrine TGF-β/miR-200b signals to maintain epithelial-mesenchymal transition in cholangiocarcinoma
Cholangiocarcinoma (CCA) is characterized by early lymphatic, metastasis, and low survival rate. Epithelial-mesenchymal transition (EMT) is able to induce tumor metastasis. Although the TGF-β/miR-200 signals p...
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Article
Open AccessSumoylation of CCAAT/enhancer-binding protein α is implicated in hematopoietic stem/progenitor cell development through regulating runx1 in zebrafish
The small ubiquitin-related modifier (SUMO) participates in various cellular processes, including maintenance of genome integrity, nuclear transport, transcription and signal transduction. However, the biologi...
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Chapter and Conference Paper
POSTER: Ciphertext-Policy Attribute-Based Encryption Method with Secure Decryption Key Generation and Outsourcing Decryption of ABE Ciphertexts
Attribute-based encryption (ABE) allows user to encrypt and decrypt data based on user attributes, and can be applied in some promising area such as mobile cloud storage. Since these are massive users in these...
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Chapter and Conference Paper
SEDOSN: A Secure Decentralized Online Social Networking Framework
Today’s online social networking services (OSN) such as Facebook, Twitter are centralized. Users’ information may be leaked by these service providers, which results in potential privacy problems. Decentralize...
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Chapter and Conference Paper
Ciphertext-Policy Attribute-Based Encryption with User and Authority Accountability
To ensure the security of sensitive data, people need to encrypt them before uploading them to the public storage. Attribute-based encryption (ABE) is a promising cryptographic primitive for fine-grained shari...
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Chapter and Conference Paper
Attribute-Based Encryption Without Key Escrow
Attribute-Based Encryption (ABE) is a promising cryptographic primitive for fine-grained sharing of encrypted data. However, ABE has a major shortcoming which is called the key escrow problem. Key generation c...
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Article
Open AccessRegulation of gene expression by FSP27 in white and brown adipose tissue
Brown and white adipose tissues (BAT and WAT) play critical roles in controlling energy homeostasis and in the development of obesity and diabetes. The mouse Fat-Specific protein 27 (FSP27), a member of the ce...
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Article
Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-α-inducible genes
Brahma-related gene 1 (BRG1 ) is a key component of the ATP-dependent chromatin-remodelling SWI2–SNF2 complex and has been implicated in regulating gene expression, cell-cycle control and tumorigenesis. Here we r...
