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    Article

    Proteomic analysis of the exosomes secreted from Ctenopharyngodon idellus kidney cells infected with grass carp reovirus reveals their involvement in the cellular responses to viral infection

    Exosomes are small membrane-enclosed vesicles secreted by various types of cells. Exosomes not only participate in different physiological processes in cells, but also involve in the cellular responses to vira...

    **ng Zhang, Yunshan Zhang, Jun Pan, Min Zhu, Zi Liang in Fish Physiology and Biochemistry (2021)

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    Article

    Tight junction protein claudin-2 promotes cell entry of Bombyx mori cypovirus

    Claudin-2 is a major component of tight junctions (TJs), which play an important role in reovirus entry into host cells. The Bombyx mori cytoplasmic polyhedosis virus (BmCPV) relates to the cypovirus strain of th...

    Min Zhu, **ng Zhang, Jun Pan, Hanxue Zhu in Applied Microbiology and Biotechnology (2021)

  3. Article

    Open Access

    Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development

    Metabolic programming and mitochondrial dynamics along with T cell differentiation affect T cell fate and memory development; however, how to control metabolic reprogramming and mitochondrial dynamics in T cel...

    Jianli He, Xun Shangguan, Wei Zhou, Ying Cao, Quan Zheng, Jun Tu in Nature Communications (2021)

  4. Article

    Open Access

    AIV polyantigen epitope expressed by recombinant baculovirus induces a systemic immune response in chicken and mouse models

    The protective efficacy of avian influenza virus (AIV) vaccines is unsatisfactory due to the presence of various serotypes generated by genetic reassortment. Thus, immunization with a polyantigen chimeric epit...

    Lei Yu, Jun Pan, Guangli Cao, Mengsheng Jiang, Yunshan Zhang, Min Zhu in Virology Journal (2020)

  5. Article

    Open Access

    Functional characterization of BmOVOs in silkworm, Bombyx mori

    In our previous study, we identified four isoforms of the Bmovo gene, Bmovo-1, Bmovo-2, Bmovo-3 and Bmovo-4 from the silkworm ovary and verified that ovarian development was regulated by the BmOVO proteins. Resul...

    Min Zhu, **aolong Hu, Zi Liang, Mengsheng Jiang, Renyu Xue, Yongchang Gong in BMC Genomics (2019)

  6. Article

    Open Access

    Clathrin-mediated endocytosis is a candidate entry sorting mechanism for Bombyx mori cypovirus

    Bombyx mori cypovirus (BmCPV), a member of the Reoviridae, specifically infects silkworms and causes extensive economic losses to the sericulture industry. To date, the entry mechanism of BmCPV into cells is uncl...

    Fei Chen, Liyuan Zhu, Yiling Zhang, Dhiraj Kumar, Guangli Cao in Scientific Reports (2018)

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    Article

    Identification of tarsal-less peptides from the silkworm Bombyx mori

    The polycistronic and non-canonical gene tarsal-less (tal, known as pri) was reported to be required for embryonic and imaginal development in Drosophila; however, there are few reports of the tal gene in the sil...

    Guangli Cao, Yongchang Gong, **aolong Hu, Min Zhu in Applied Microbiology and Biotechnology (2018)

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    Article

    Exogenous gene can be expressed by a recombinant Bombyx mori cypovirus

    Bombyx mori cypovirus (BmCPV) is one of the major viral pathogen for silkworm, and the genome of BmCPV is composed of 10 dsRNA segments. As construction system of recombinant BmCPV (rBmCPV) is sc...

    Rui Guo, Guangli Cao, Renyu Xue, Dhiraj Kumar in Applied Microbiology and Biotechnology (2018)

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    Article

    Performance evaluation and microbial community analysis of the function and fate of ammonia in a sulfate-reducing EGSB reactor

    Ammonia is widely distributed in sulfate-reducing bioreactor dealing with sulfate wastewater, which shows potential effect on the metabolic pathway of sulfate and ammonia. This study investigates the sulfate-r...

    Depeng Wang, Bo Liu, **nchun Ding, **nbo Sun in Applied Microbiology and Biotechnology (2017)

  10. Article

    Open Access

    Effects of transient high temperature treatment on the intestinal flora of the silkworm Bombyx mori

    The silkworm Bombyx mori is a poikilotherm and is therefore sensitive to various climatic conditions. The influence of temperature on the intestinal flora and the relationship between the intestinal flora and gen...

    Zhenli Sun, Dhiraj Kumar, Guangli Cao, Liyuan Zhu, Bo Liu, Min Zhu in Scientific Reports (2017)

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    Article

    Proteomic analysis of BmN cell lipid rafts reveals roles in Bombyx mori nucleopolyhedrovirus infection

    The mechanism of how Bombyx mori nucleopolyhedrovirus (BmNPV) enters cells is unknown. The primary components of membrane lipid rafts are proteins and cholesterol, and membrane lipid rafts are thought to be an ac...

    **aolong Hu, Min Zhu, Zi Liang, Dhiraj Kumar, Fei Chen in Molecular Genetics and Genomics (2017)

  12. No Access

    Article

    Effect of BBX-B8 overexpression on development, body weight, silk protein synthesis and egg diapause of Bombyx mori

    Bombyxin (BBX) is an insulin-like peptide exists in the silkworm Bombyx mori. Our previous studies on the effects of inhibiting BBX-B8 expression found that BBX-B8 is important for the development of organ, repro...

    **aojian Zheng, Yongchang Gong, Dhiraj Kumar, Fei Chen, Sulan Kuan in Transgenic Research (2016)

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    Article

    Mechanical properties and network structure of hydrophobic association hydrogels prepared from octylphenol polyoxyethylene(7) acrylate and sodium dodecyl sulfate

    Hydrophobic association hydrogels(HA-gels) with high mechanical strength were prepared by free radical micellar copolymerization in aqueous solutions of acrylamide(AM), anion surfactant sodium dodecyl sulfate(...

    Zi Liang, Tingting Gao, Jianan Xu, Zhiying Li in Chemical Research in Chinese Universities (2015)

  14. No Access

    Article

    The gene expression profile of resistant and susceptible Bombyx mori strains reveals cypovirus-associated variations in host gene transcript levels

    High-throughput paired-end RNA sequencing (RNA-Seq) was performed to investigate the gene expression profile of a susceptible Bombyx mori strain, Lan5, and a resistant B. mori strain, Ou17, which were both orally...

    Rui Guo, Simei Wang, Renyu Xue, Guangli Cao in Applied Microbiology and Biotechnology (2015)