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Article
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro
Although it is known that caffeic acid phenethyl ester (CAPE) and its derivatives could ameliorate acute myocardial injury, their effects on chronic myocardial ischemia (CMI) were not reported. This study aime...
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Article
Open AccessCold acclimation can specifically inhibit chlorophyll biosynthesis in young leaves of Pakchoi
Leaf color is an important trait in breeding of leafy vegetables. Y-05, a pakchoi (Brassica rapa ssp. chinensis) cultivar, displays yellow inner (YIN) and green outer leaves (GOU) after cold acclimation. However,...
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Article
Open AccessAnti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites
Caffeic acid phenethyl ester (CAPE), extracted from propolis, was proven to inhibit colon cancer. Caffeic acid p-nitro-phenethyl ester (CAPE-pNO2), a derivative of CAPE, was determined to be an anti-platelet agen...
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Article
Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells
The medical properties of baicalin have been well known for many years. However, the discovery that baicalin in the presence of metal ions is more effective than baicalin alone changed the course of drug resea...
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Article
Effect of diallyl trisulfide derivatives on the induction of apoptosis in human prostate cancer PC-3 cells
The effects of five derivatives of diallyl trisulfide (DATS) were investigated on apoptosis in prostate cancer PC-3 cells, including dibutenyl trisulfide (DBTS), bis(2-methylallyl) trisulfide (2-M-DATS), dipen...
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Article
Synthesis of novel analogues on the α-carbon of houttuyfonate and SAR analysis of antibacterial activity with MOPAC
Three novel α-carbon derivatives of houttuyfonate—HOU-C8C1, HOU-C8C2, and HOU-C8C4—were designed and synthesized, and tested for their in vitro antibacterial activities against seven bacterial strains. A set of m...