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  1. Article

    Open Access

    MRI radiomics enhances radiologists’ ability for characterizing intestinal fibrosis in patients with Crohn’s disease

    We aimed to develop MRI-based radiomic models (RMs) to improve the diagnostic accuracy of radiologists in characterizing intestinal fibrosis in patients with Crohn’s disease (CD).

    Mengchen Zhang, Yinghou Zeng, Zhuang-nian Fang, Yang-di Wang in Insights into Imaging (2024)

  2. No Access

    Article

    Magnetisation transfer imaging adds information to conventional MRIs to differentiate inflammatory from fibrotic components of small intestinal strictures in Crohn’s disease

    Identifying inflammation- or fibrosis-predominant strictures in Crohn’s disease (CD) is crucial for treatment strategies. We evaluated the additive value of magnetisation transfer (MT) to conventional MRI for ...

    Zhuang-nian Fang, Xue-hua Li, **-jiang Lin, Si-yun Huang in European Radiology (2020)

  3. Article

    Open Access

    A novel collagen area fraction index to quantitatively assess bowel fibrosis in patients with Crohn’s disease

    A validated histopathological tool to precisely evaluate bowel fibrosis in patients with Crohn’s disease is lacking. We attempted to establish a new index to quantify the severity of bowel fibrosis in patients...

    Xue-hua Li, Zhuang-nian Fang, Tian-ming Guan, **-jiang Lin in BMC Gastroenterology (2019)

  4. No Access

    Article

    IVIM with fractional perfusion as a novel biomarker for detecting and grading intestinal fibrosis in Crohn’s disease

    Intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) provides information on both perfusion and diffusion and has been used to evaluate Crohn’s disease (CD) activity and fibr...

    Meng-Chen Zhang, Xue-Hua Li, Si-Yun Huang, Ren Mao, Zhuang-Nian Fang in European Radiology (2019)

  5. No Access

    Article

    Ability of DWI to characterize bowel fibrosis depends on the degree of bowel inflammation

    Although diffusion-weighted imaging (DWI) is reported to be accurate in detecting bowel inflammation in Crohn’s disease (CD), its ability to assess bowel fibrosis remains unclear. This study assessed the role ...

    Xue-hua Li, Ren Mao, Si-yun Huang, Zhuang-nian Fang, Bao-Lan Lu in European Radiology (2019)