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Article
Fibroblast-localized lncRNA CFIRL promotes cardiac fibrosis and dysfunction in dilated cardiomyopathy
CFIRL is a long noncoding RNA (lncRNA), we previously identified as the most significantly upregulated lncRNA in the failing hearts of patients with dilated cardiomyopathy (DCM). In this study, we determined t...
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Chapter and Conference Paper
Crack Analysis and Improvement of Helicopter Engine Compartment Partition
The crack on the engine compartment partition of a helicopter continually occurs, which has affected the flight safety. First, the simplified modeling of engine and local structure detail modeling are studied....
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Chapter and Conference Paper
Cabin Noise Analysis and Noise Reduction Design of the Helicopter with Double-Swept Rotor Blade
The double-swept rotor blade is a new type of blade, and its vortex interference noise level is lower than that of traditional blade. In this paper, the contribution of the cabin noise source of a helicopter i...
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Chapter and Conference Paper
Research on Influence of Dynamic Balance Deviation on Blade Static Stiffness and Airframe Vibration
During the maintenance and adjustment process of a helicopter blade returning to the factory, the dynamic balance parameters are often deviated and the blades cannot be delivered to users on time. In this pape...
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Article
The Effects of Microstructure on Mechanical Properties of Tin-Based Bearing Alloy Based on Finite Element Modeling
Researches have shown that the mechanical properties of bearing alloy depend to a large extent on its microstructure and the morphology and quantity of each constituent phase. In order to study the effects of ...
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Article
Open AccessA Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy
Dilated cardiomyopathy (DCM) is the leading cause of heart transplantation. By microRNA (miRNA) array, a Kaposi’s sarcoma-associated herpes virus (KSHV)-encoded miRNA, kshv-miR-K12-1-5p, was detected in patien...
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Article
A cross-scale analysis method for predicting the compressive mechanical properties of tin-based bearing alloy
A cross-scale analysis method for predicting the compressive mechanical properties of tin-based bearing alloy was proposed based on microstructure finite element simulation and molecular dynamics (MD) simulati...
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Article
Biological Functions and Clinical Prospects of Extracellular Non-Coding RNAs in Diabetic Cardiomyopathy: an Updated Review
Diabetic cardiomyopathy (DCM) is one of the major causes of heart failure in diabetic patients. However, the pathogenesis of diabetic cardiomyopathy has not been fully elucidated. Diagnosis and therapeutic str...
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Article
New high-density fermentation method for producing high molecular weight polysialic acid based on the combination fermentation strategy
Polysialic acid (PSA) is a long-chain linear amino polysaccharide with broad application prospects; however, its relatively low molecular weight limits its application range. This study aims to explore a new f...
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Article
Simulation Study on Filling and Solidification of Horizontal Centrifugal Casting Babbitt Lining of Bimetallic Bearing
A continuous flow model to simulate the horizontal centrifugal casting was built based on the numerical simulation technique of filling and solidification processes, which realized the continuous simulation of...
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Article
Open AccessMiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα
Metabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac metabolic disorder in DCM were not fully understood.
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Article
Open AccessMiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin
Diabetes is a leading cause of mortality and morbidity across the world. Over 50% of deaths among diabetic patients are caused by cardiovascular diseases. Cardiac diastolic dysfunction is one of the key early ...
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Article
Open AccessCirculating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans
Recently, plasma miRNAs have been reported as biomarkers for various diseases. However, the knowledge on the association of plasma miRNAs with ischemic stroke is still lacking. In this study, we investigated w...
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Article
Impaired NK cell antiviral cytokine response against influenza virus in small-for-gestational-age neonates
The neonates, particularly small-for-gestational-age (SGA) ones, are susceptible to various microbial infections. Natural killer (NK) cells are critical components of host innate immunity system and the main s...
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Article
Vγ9Vδ2-T lymphocytes have impaired antiviral function in small-for-gestational-age and preterm neonates
Preterm and small-for-gestational-age (SGA) neonates are vulnerable groups that are susceptible to various microbial infections. Vγ9Vδ2-T cells are critical components of the host immune system and have been d...
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Article
Human Vγ9Vδ2-T cells efficiently kill influenza virus-infected lung alveolar epithelial cells
γδ-T cells play an indispensable role in host defense against different viruses, including influenza A virus. However, whether these cells have cytotoxic activity against influenza virus-infected lung alveolar...
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Article
Roles of Surface Booster System on Bending of Thin-Walled Copper Tube
Thin-walled C12200 circular copper tube has been widely used in HVAC (heating, ventilation, air conditioning, and refrigeration) industry. Rotary draw bending is a versatile and precise method in forming of th...
