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  1. Article

    Open Access

    Efficacy evaluation of chimeric antigen receptor-modified human peritoneal macrophages in the treatment of gastric cancer

    Gastric cancer is one of the most common cancers. Peritoneal carcinomatosis (PC) appears to be the most common pattern of recurrence, and more than half of the GC patients eventually die from PC. Novel strateg...

    Xuhui Dong, Jiqiang Fan, Wangxu **e, **ang Wu, Jia Wei in British Journal of Cancer (2023)

  2. Article

    Open Access

    Cold Atmospheric Plasma Stimulates Clathrin-Dependent Endocytosis to Repair Oxidised Membrane and Enhance Uptake of Nanomaterial in Glioblastoma Multiforme Cells

    Cold atmospheric plasma (CAP) enhances uptake and accumulation of nanoparticles and promotes synergistic cytotoxicity against cancer cells. However, the mechanisms are not well understood. In this study, we in...

    Zhonglei He, Kangze Liu, Laurence Scally, Eline Manaloto in Scientific Reports (2020)

  3. Article

    Open Access

    Cold Atmospheric Plasma induces accumulation of lysosomes and caspase-independent cell death in U373MG glioblastoma multiforme cells

    Room temperature Cold Atmospheric Plasma (CAP) has shown promising efficacy for the treatment of cancer but the exact mechanisms of action remain unclear. Both apoptosis and necrosis have been implicated as th...

    Gillian E. Conway, Zhonglei He, Ana Lacramioara Hutanu in Scientific Reports (2019)

  4. Article

    Open Access

    A novel, rapid, seedless, in situ synthesis method of shape and size controllable gold nanoparticles using phosphates

    We hereby report a novel synthesis method of size and shape controllable gold nanoparticles that is rapid, in situ and seedless. Unlike most currently employed size and shape controllable synthesis methods, it ta...

    Kangze Liu, Zhonglei He, James F. Curtin, Hugh J. Byrne, Furong Tian in Scientific Reports (2019)

  5. Article

    Open Access

    Cold Atmospheric Plasma Induces ATP-Dependent Endocytosis of Nanoparticles and Synergistic U373MG Cancer Cell Death

    Gold nanoparticles (AuNP) have potential as both diagnostic and therapeutic vehicles. However, selective targeting and uptake in cancer cells remains challenging. Cold atmospheric plasma (CAP) can be combined ...

    Zhonglei He, Kangze Liu, Eline Manaloto, Alan Casey in Scientific Reports (2018)