7 Result(s)
within
Zhong-ming Qian
Cardiology
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Article
Iron and Intracerebral Hemorrhage: From Mechanism to Translation
Intracerebral hemorrhage (ICH) is a leading cause of morbidity and mortality around the world. Currently, there is no effective medical treatment available to improve functional outcomes in patients with ICH d...
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Article
Identification of transcriptionally regulated genes in response to cellular iron availability in rat hippocampus
The present study was attempted to identify transcriptionally regulated genes of the normal neurocytes responsive to iron availability. Postnatal rat hippocampus cells were primarily cultured either under the ...
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Article
Molecular analysis of increased iron status in moderately exercised rats
Although iron plays a critical role in exercise, the regulatory mechanism of iron metabolism remains poorly understood. The aims of the present study were to investigate the effects of different intensity exer...
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Article
Nitric oxide inhibition decreases bleomycin-detectable iron in spleen, bone marrow cells and heart but not in liver in exercise rats
The possible role of nitric oxide on the exercise-induced changes in bleomycin-detectable iron (BDI) in the liver, spleen, bone marrow cells and heart was investigated. Female Sprague—Dawley rats were randomly...
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Article
Genistein protects primary cortical neurons from iron-induced lipid peroxidation
Neuroprotective role of isoflavones in particular genistein might be resulted from their antioxidant activities in addition to their estrogenic actions. In the present study, we investigated effect of genistei...
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Article
Hydrogen peroxide enhanced inron-induced injury in isolated heart and ventricular cardiomyocyte in rats
To explore the cardiac effects of iron with or without hydrogen peroxide, the isolated perfused rat heart and enzymatically isolated ventricular cardiomyocyte were used. It was shown that treatment with cell-p...
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Article
Inhibitory mechanism of lead on transferrin-bound iron uptake by rabbit reticulocytes: A fractal analysis
Experimental data of transferrin and transferrin-bound iron uptake byrabbit reticulocytes in the presence or absence of extracellular lead isanalyzed by means of a fractal model. A highly significant correlati...
