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  1. Article

    Open Access

    SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis

    Human hexokinase 2 is an essential regulator of glycolysis that couples metabolic and proliferative activities in cancer cells. The binding of hexokinase 2 to the outer membrane of mitochondria is critical for...

    Xun Shangguan, Jianli He, Zehua Ma, Weiwei zhang, Yiyi Ji in Nature Communications (2021)

  2. Article

    Open Access

    Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops

    Excessive RANKL signaling leads to superfluous osteoclast formation and bone resorption, is widespread in the pathologic bone loss and destruction. Therefore, targeting RANKL or its signaling pathway has been ...

    **g Li, Li Zeng, Juan **e, Zhiying Yue, Huayun Deng, Xueyun Ma in Scientific Reports (2015)