-
Article
Effects of microsolvation and aqueous solvation on the tautomers of histidine: a computational study on energy, structure and IR spectrum
Microsolvation and combined microsolvation-continuum approaches are employed to investigate the structures and energies of canonical and zwitterionic histidine conformers. The effect of hydration on the relati...
-
Article
Transport and Magnetic Properties of K0.8Fe2−x Cu x Se2(0 ⩽ x ⩽ 2) System
We have grown a series of high-quality single crystals of K0.8Fe2−x Cu x Se2(0 ⩽ x ⩽ 2) by Bridgman method and investigated their physical properties by measureme...
-
Article
Systematic theoretical investigation of structures, stabilities, and electronic properties of rhodium-doped silicon clusters: Rh2Si n q (n = 1–10; q = 0, ±1)
A systematic investigation of rhodium-doped silicon clusters, Rh2Si n q with n ...
-
Article
Open AccessSingle-indicator-based Multidimensional Sensing: Detection and Identification of Heavy Metal Ions and Understanding the Foundations from Experiment to Simulation
Multidimensional sensing offers advantages in accuracy, diversity and capability for the simultaneous detection and discrimination of multiple analytes, however, the previous reports usually require complicate...
-
Article
Open AccessProtein-directed synthesis of highly monodispersed, spherical gold nanoparticles and their applications in multidimensional sensing
An in-situ reduction method has been reported to prepare gold nanoparticles (GNPs) of 40–110 nm by using the green reducing agents of proteins, which are activated by H2O2 and the superoxide anion ( ...
-
Article
Probing the structures, stabilities, and electronic properties of neutral and charged carbon-doped lithium CLi n μ (n = 2–20, μ = 0, ±1) clusters from unbiased CALYPSO method
The structural and electronic properties of the global minimum structures of neutral, anionic and cationic CLi n μ ...
-
Article
Open AccessDiagnostic performance of Contrast-enhanced CT in Pyrrolizidine Alkaloids-induced Hepatic Sinusoidal Obstructive Syndrome
Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by pyrrolizidine alkaloids(PAs)-containing herbals. Since PAs exposure is obscure and clinical presentation of HSOS is unspecific, it is challenge t...
-
Article
The effects of colorimetric detection of heavy metal ions based on Au nanoparticles (NPs): size and shape—a case of Co2+
The different sized and shaped Au NPs have intrigued considerable attention, because they possess different surface plasma resonance (SPR) absorption bands and thus result in many colorimetric Au NP-based dete...
-
Article
Open Accessβ2 spectrin-mediated differentiation repressed the properties of liver cancer stem cells through β-catenin
βII-Spectrin (β2SP), a Smad3/4 adaptor protein during transforming growth factor (TGF) β/Smad signal pathway, plays a critical role in suppressing hepatocarcinogenesis. Dedifferentiation is a distinctive featu...
-
Article
Experimental Study of Phase Relations in the Mg-Er-Si System Focused on Mg-Rich Region at 300 and 400 °C
The phase equilibria and compositions in the magnesium (Mg) rich part of the Mg-Er-Si ternary system at 300 and 400 °C were systemically investigated through the equilibrated alloy method by using x-ray diffra...
-
Article
Sub-10-nm multicolored gold nanoparticles for colorimetric determination of antibiotics via formation of interlocking rings
A general approach is presented for synthesis of multicolored gold nanoparticles (GNPs) by Au(I)-mediated generation of interlocking rings in proteins and antibiotics. The Au(I) ions are shuttled from proteins...
-
Article
Open AccessMyofibroblast induces hepatocyte-to-ductal metaplasia via laminin–ɑvβ6 integrin in liver fibrosis
Hepatocytes undergo the metaplasia into ductal biliary epithelial cells (BECs) in response to chronic injury, and subsequently contribute to liver regeneration. The mechanism underlying hepatocyte-to-ductal me...
-
Article
Open AccessPrognostic factors for ARDS: clinical, physiological and atypical immunodeficiency
Risk factors affecting the prognosis of acute respiratory distress syndrome (ARDS) in adults were investigated. The aim was to identify new predictors for ARDS patient prognosis, including those with clinical,...
-
Article
The development and understanding of intracranial aneurysm based on rabbit model
In modern society, intracranial aneurysms have seriously affected people’s life. To better study and treat intracranial aneurysm, animal models are ideal candidates to perform biological research and preclinic...
-
Article
A rapid reduction of Au(I→0) strategy for the colorimetric detection and discrimination of proteins
A gold nanoparticle (AuNP)–based sensing strategy based on rapid reduction of Au(I→0) is proposed. As a proof-of-concept study, the proposed sensing principle is designed for simultaneous and colorimetric dete...
-
Article
Open AccessUnderlying mechanism of hemodynamics and intracranial aneurysm
In modern society, subarachnoid hemorrhage, mostly caused by intracranial aneurysm rupture, is accompanied by high disability and mortality rate, which has become a major threat to human health. Till now, the ...
-
Article
SDF-1α/CXCR4 Pathway Mediates Hemodynamics-Induced Formation of Intracranial Aneurysm by Modulating the Phenotypic Transformation of Vascular Smooth Muscle Cells
The objective of this study is to explore the role of the SDF-1α/CXCR4 pathway in the development of intracranial aneurysm (IA) induced by hemodynamic forces. We collected 12 IA and six superficial temporal ar...
-
Article
Open AccessCMIC: an efficient quality score compressor with random access functionality
Over the past few decades, the emergence and maturation of new technologies have substantially reduced the cost of genome sequencing. As a result, the amount of genomic data that needs to be stored and transmi...
-
Article
SnO Nanosheets As an Efficient Electrocatalyst for Carbon Dioxide Reduction
Electrochemical carbon dioxide (CO2) reduction to fuels or chemicals is a promising route to offset the over discharged CO2, where efficient electrocatalysts are desirable. In this study, we synthesized SnO nanos...
-
Article
Association Between Regular Blood Pressure Monitoring and the Risk of Intracranial Aneurysm Rupture: a Multicenter Retrospective Study with Propensity Score Matching
Although hypertension is a known risk factor for intracranial aneurysm rupture, the benefit of the management of blood pressure in reducing the rupture risk of intracranial aneurysms remains largely unknown, e...
