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Article
miR-219-5p attenuates cisplatin resistance of ovarian cancer by inactivating Wnt/β-catenin signaling and autophagy via targeting HMGA2
Our previous study confirmed that miR-219-5p inhibits the progression of ovarian cancer (OC) by targeting high mobility group AT-hook 2 (HMGA2), while the role of miR-219-5p on the chemoresistance of OC is unc...
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Article
Relationship between bitumen and zinc–lead mineralization in the Nanmushu zinc–lead deposit, northern margin of Sichuan Basin, China
The Nanmushu zinc–lead deposit is hosted by the Dengying Formation (Z2dn) and lies on the northern margin of Sichuan Basin, China. The deposit is a Mississippi Valley-type (MVT) lead–zinc deposit associated with ...
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Article
Geology, fluid inclusion, bitumen and isotope geochemistry of the organic-matter-rich Nanmushu lead–zinc deposit, Mayuan, the northern margin of the Yangtze platform, China
The Nanmushu lead–zinc deposit is located in the northern margin of Yangtze plate, midwest China. Ore bodies are hosted in Sinian carbonate rocks, which is controlled by the Sinian Dengying Formation. Metal mi...
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Article
Mineralogy, fluid inclusions, H-O isotopes, and trace element of the Dongzigou Pb-Zn deposit in the Sangmuchang metallogenic belt, China
The Dongzigou Pb-Zn deposit is located in the south-eastern margin of Yangtze block, Midwest China. Ore bodies are hosted in Sinian carbonate rocks. The main metallic minerals are sphalerite and galena, while ...
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Article
Open AccessMiR-219-5p inhibits growth and metastasis of ovarian cancer cells by targeting HMGA2
Accumulating studies have demonstrated that high-mobility group A2 (HMGA2), an oncofetal protein, plays a role in tumor development and progression. However, the molecular role of HMGA2 in ovarian carcinoma is...
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Article
Open AccessThe first identification of genomic loci in plants associated with resistance to galling insects: a case study in Eucalyptus L'Hér. (Myrtaceae)
Genomic loci related with resistance to gall-inducing insects have not been identified in any plants. Here, association map** was used to identify molecular markers for resistance to the gall wasp Leptocybe inv...
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Article
Open AccessGenome scans for divergent selection in natural populations of the widespread hardwood species Eucalyptus grandis (Myrtaceae) using microsatellites
Identification of loci or genes under natural selection is important for both understanding the genetic basis of local adaptation and practical applications, and genome scans provide a powerful means for such ...
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Article
Open AccessDiSNPindel: improved intra-individual SNP and InDel detection in direct amplicon sequencing of a diploid
Amplicon re-sequencing based on the automated Sanger method remains popular for detection of single nucleotide polymorphisms (SNPs) and insertion-deletion polymorphisms (InDels) for a spectrum of genetics appl...
