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  1. Article

    Open Access

    Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models

    Sorafenib is recognized as a standard treatment for advanced hepatocellular carcinoma (HCC). However, many patients have to adopt dose reduction or terminate the use of sorafenib because of side effects. In ad...

    Abin You, Manqing Cao, Zhigui Guo, Bingfeng Zuo in Journal of Hematology & Oncology (2016)

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    Article

    HIF-2α regulates CDCP1 to promote PKCδ-mediated migration in hepatocellular carcinoma

    Overexpression of CUB domain-containing protein 1 (CDCP1), a transmembrane glycoprotein and major substrate of Src family kinases (SFKs), always indicates unfavorable outcomes in various cancers. The character...

    Manqing Cao, Junrong Gao, Hongyuan Zhou, Jiafei Huang, Abin You in Tumor Biology (2016)