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Article
Open AccessPrevalence of Neutralizing Autoantibodies Against Type I Interferon in a Multicenter Cohort of Severe or Critical COVID-19 Cases in Shanghai
We sought to explore the prevalence of type I interferon-neutralizing antibodies in a Chinese cohort and its clinical implications during the Omicron variant wave of SARS-CoV-2.
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Article
Effects of wet torrefaction on physicochemical properties of dark tea residue and pyrolysis products
In this study, dark tea residue (DTR) and polypropylene (PP) were used as the experimental raw material, and the method that combined wet torrefaction (hydrothermal carbonization) and pyrolysis was used to ana...
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Article
Combined application of biochar and magnesium fertilizer effectively improved the soil environment and the tea quality in southern strongly acidic tea garden
Soil acidification and magnesium (Mg) deficiency are common in tea gardens in southern China. The application of Mg fertilizer and biochar combined with fertilizer is considered as one of the effective agronom...
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Article
Effects of the combined application of biochar-based fertilizer and urea on N2O emissions, nitrifier, and denitrifier communities in the acidic soil of pomelo orchards
Nitrous oxide (N2O) is a greenhouse gas generated from nitrification and denitrification in the soil, and fertilizers may affect its emission. In this study, the effects of the combined application of a biochar-b...
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Article
Discovery of potential anti-SARS-CoV-2 drugs based on large-scale screening in vitro and effect evaluation in vivo
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global crisis. Clinical candidates with high efficacy, ready availability, and that ...
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Article
Molecular epidemiology and clinical characterization of human rhinoviruses circulating in Shanghai, 2012-2020
Human rhinoviruses (HRVs) cause acute upper and lower respiratory tract infections and aggravation of asthma and chronic obstructive pulmonary disease. The 5’ untranslated region (5' UTR) and the VP4/VP2 regio...
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Article
Open AccessInfluenza A Virus (H1N1) Infection Induces Glycolysis to Facilitate Viral Replication
Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their replication. In this study, we observed that influenza A virus (H1N1), a single-stranded, ne...
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Article
Open AccessPotential transmission chains of variant B.1.1.7 and co-mutations of SARS-CoV-2
The presence of SARS-CoV-2 mutants, including the emerging variant B.1.1.7, has raised great concerns in terms of pathogenesis, transmission, and immune escape. Characterizing SARS-CoV-2 mutations, evolution, ...
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Article
Nitrogen addition inhibits total monoterpene emissions in subtropical forest floor of South China
Monoterpenes (MTs) play crucial roles not only in atmospheric chemistry and global climate change but also in soil processes and soil ecology. Elevated nitrogen (N) deposition can influence soil microbial comm...
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Article
Open AccessA streamlined clinical metagenomic sequencing protocol for rapid pathogen identification
Metagenomic next-generation sequencing (mNGS) holds promise as a diagnostic tool for unbiased pathogen identification and precision medicine. However, its medical utility depends largely on assay simplicity an...
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Article
The Establishment of Infectious Clone and Single Round Infectious Particles for Coxsackievirus A10
Coxsackievirus A10 (CVA10) is one of the major etiological agents of hand, foot, and mouth disease. There are no vaccine and antiviral drugs for controlling CVA10 infection. Reverse genetic tools for CVA10 wil...
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Article
Viral and host factors related to the clinical outcome of COVID-19
In December 2019, coronavirus disease 2019 (COVID-19), which is caused by the new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan (Hubei province, China)1; it soo...
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Article
Foliage application of nitrogen has less influence on soil microbial biomass and community composition than soil application of nitrogen
Many studies have shown the simulated effects of nitrogen (N) deposition on soil microbial community composition by adding N directly to the forest floor but have ignored the N retention process by the canopy....
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Hepatitis C Virus-Associated Cancers
Most hepatitis C virus (HCV) infection results in persistent infection. Significant portion of chronic HCV-infected patients develop hepatocellular carcinoma (HCC). Chronic hepatitis C is also associated with ...
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Article
Occurrence of Decabromodiphenyl Ethane in Captive Chinese Alligators (Alligator sinensis) from China
Decabromodiphenyl ethane (DBDPE), a replacement for decabromodiphenyl ether (deca-BDE), was investigated in captive Chinese alligators from China. DBDPE was detected in adult tissues, neonates and eggs of Chin...
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Article
Evaluation of photocatalytic production of active oxygen and decomposition of phenol in ZnO suspensions
Photocatalytic production of hydroxyl radical (·OH) and superoxide anion (·O2 −) and decomposition of phenol in ZnO suspensions were studied in the present paper. Nano-sized ZnO (n-ZnO) pr...
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Article
Photocatalytic activity and stability of ZnO particles with different morphologies
Phenol was used as a probe molecule to evaluate the photocatalytic activity of three kinds of zinc oxides, t-ZnO (tetra-needle like ZnO), n-ZnO (nano-sized particle) and c-ZnO (micro-sized particle). The photo...
