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Article
Preparation and characterization of nanostructured Al2O3-13wt.%TiO2 ceramic coatings by plasma spraying
Nanostructured and conventional Al2O3-13wt.%TiO2 ceramic coatings were prepared by plasma spraying with nanostructured agglomerated and conventional powders, respectively. The microstructure and microhardness of ...
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Article
Overexpression of cyclin Y in non-small cell lung cancer is associated with cancer cell proliferation
Cyclin Y (CCNY) is a key cell cycle regulator that acts as a growth factor sensor to integrate extracellular signals with the cell cycle machinery. The expression status of CCNY in lung cancer and its clinical...
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Article
Subcortical origins of human and monkey neocortical interneurons
In primates, the developmental origin of neocortical interneurons is controversial. Here the authors map out expression patterns of key transcription factors in the develo** human and monkey brain and reveal...
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Article
Mixed Polyethylene Glycol-Modified Breviscapine-Loaded Solid Lipid Nanoparticles for Improved Brain Bioavailability: Preparation, Characterization, and In Vivo Cerebral Microdialysis Evaluation in Adult Sprague Dawley Rats
Breviscapine is used in the treatment of ischemic cerebrovascular diseases, but it has a low bioavailability in the brain due to its poor physicochemical properties and the activity of P-glycoprotein efflux pu...
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Article
Open AccessVideo-assisted thoracic bronchial sleeve lobectomy with bronchoplasty for treatment of lung cancer confined to a single lung lobe: a case series of Chinese patients
The outcomes of video-assisted thoracic bronchial sleeve lobectomy (VABSL), a minimally invasive video-assisted thoracoscopic (VATS) lobectomy, are mostly unknown in Chinese patients.
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Article
Research on the influence of dielectric characteristics on the EDM of titanium alloy
This study investigated the influences of dielectric characteristics, namely, electrical conductivity, oxidability, and viscosity on the electrical discharge machining (EDM) of titanium alloy. A new kind of co...
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Article
Design of high-performance integrated dimmable LED driver for high-brightness solid-state lighting applications
This paper presents a high-voltage buck-type dimmable LED driver for high-brightness solid-state lighting applications. A synchronous hysteretic current control (SHCC) scheme is developed to regulate the LED c...
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Article
Deep-type hole machining by inner jetted aerosol dielectric ablation
To improve the stability and technological index for deep hole machining by electrical discharge machining (EDM), this study proposed a hole machining method that employs continuous flushing and intermittent o...
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Article
Machining characteristics of hard and brittle insulating materials with mist-jetting electrochemical discharge
A new electrochemical discharge machining (EDM) method that combines slotted metal wheel and mist-jetting electrolyte was proposed based on existing problems in the traditional electrolytic EDM compound machin...
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Article
Open AccessSleeve lobectomy by video-assisted thoracic surgery versus thoracotomy for non-small cell lung cancer
Both video-assisted thoracic surgery (VATS) and thoracotomy are used for sleeve lobectomy for patients with non-small cell lung cancer (NSCLC). This retrospective study aimed to assess the safety and efficacy ...
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Article
Open AccessMycobacterium Lysine ε-aminotransferase is a novel alarmone metabolism related persister gene via dysregulating the intracellular amino acid level
Bacterial persisters, usually slow-growing, non-replicating cells highly tolerant to antibiotics, play a crucial role contributing to the recalcitrance of chronic infections and treatment failure. Understandin...
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Article
Influence of discharge energy on EDM ablation
In the process of electrical discharge machining (EDM) ablation, discharge energy can heat the materials, activate the surface, and eliminate metal corrosion. We study the discharge energy by building an ablat...
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Article
Study of multi-cutting by WEDM for specific crystallographic planes of monocrystalline silicon
In this study, multi-cutting technology by wire electrical discharge machining (WEDM) for metal material processing is applied to cut semiconductor monocrystalline silicon with specific crystal orientation, wh...
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Article
Open AccessPotential advantages of a novel chitosan-N-acetylcysteine surface modified nanostructured lipid carrier on the performance of ophthalmic delivery of curcumin
The transient precorneal retention time and low penetration capacity into intraocular tissues are the key obstacles that hinder the ophthalmic drug delivery of many therapeutic compounds, especially for drugs ...
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Article
Thickness measurement of deterioration layer of monocrystalline silicon by specific crystallographic plane cutting of wire electrical discharge machining
The thickness of the deterioration layer in the specific crystallographic plane of monocrystalline silicon, which was processed under different conditions of wire-cut electrical discharge machining (WEDM), was...
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Article
Monopulse electrical discharge machining ablation drilling technology for Ti-6Al-4V titanium alloy
A high-current monopulse electrical discharge machining (EDM) discharge ablation technique (i.e., monopulse EDM ablation) to drill Ti-6Al-4V titanium alloy plates is proposed. The activated surface material th...
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Article
Association between flood and the morbidity of bacillary dysentery in Zibo City, China: a symmetric bidirectional case-crossover study
This study examined the relationship between daily morbidity of bacillary dysentery and flood in 2007 in Zibo City, China, using a symmetric bidirectional case-crossover study. Odds ratios (ORs) and 95 % confi...
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Article
Open AccessScreening the active compounds of Phellodendri Amurensis cortex for treating prostate cancer by high-throughput chinmedomics
Screening the active compounds of herbal medicines is of importance to modern drug discovery. In this work, an integrative strategy was established to discover the effective compounds and their therapeutic tar...
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Article
LincRNa-p21: function and mechanism in cancer
In view of the rapid development of gene chips and high-throughput sequencing technology, noncoding RNAs (ncRNas) form a high percentage of the mammalian genome. Two major subgroups of ncRNAs that have been id...
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Article
Machining damage of monocrystalline silicon by specific crystallographic plane cutting of wire electrical discharge machining
The machining damage on the certain crystal face of single crystal silicon, the manufacture of which are under diverse parameters of wire electrical discharge machining (WEDM), is tested by means of the micro-...
