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Article
Open AccessA multidimensional nomogram combining clinical factors and imaging features to predict 1-year recurrence of low back pain with or without radicular pain after spinal manipulation/mobilization
In this retrospective study, we aimed to develop a nomogram to predict recurrence during a 1-year period of spinal manipulation/mobilization (SM/M) in patients with low back pain (LBP) with greater pain intens...
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Article
Stellar initial mass function varies with metallicity and time
Most structural and evolutionary properties of galaxies strongly rely on the stellar initial mass function (IMF), namely the distribution of the stellar mass formed in each episode of star formation1–4. The IMF s...
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Article
Open AccessSingle-cell DNA methylation sequencing reveals epigenetic alterations in mouse oocytes superovulated with different dosages of gonadotropins
Epigenetic abnormalities caused by superovulation have recently attracted increasing attention. Superovulation with exogenous hormones may prevent oocytes from establishing an appropriate epigenetic state, and...
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Article
Open AccessEffect of exogenous gonadotropin on the transcriptome of human granulosa cells and follicular fluid hormone profiles
Superovulation treatment had some adverse effects on maturity and development of oocytes. Can superovulation dose of gonadotropins (Gns) affect the transcriptome of granulosa cells and follicular fluid (FF) ho...
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Article
Endothelial Insulin-Like Growth Factor-1 Modulates Proliferation and Phenotype of Smooth Muscle Cells Induced by Low Shear Stress
Endothelial cells (ECs) are directly exposed to shear stress and modulate the neighboring vascular smooth muscle cells (VSMCs), which plays important roles in vascular remodeling during atherosclerosis. Our pr...
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Article
Effect of stacking type in precursors on composition, morphology and electrical properties of the CIGS films
The copper-indium-gallium (CIG) metallic precursors with different stacking type (A: CuGa/CuIn/CuGa/glass and B: CuInGa/CuIn/CuInGa/glass) were prepared onto glass substrates by magnetron sputtering method. In...
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Article
A novel 7-O-modified genistein derivative with acetylcholinesterase inhibitory effect, estrogenic activity and neuroprotective effect
To find the multi-target-directed compounds for the treatment of Alzheimer’s disease (AD), we synthesized 7-(4-(diethylamino)butoxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, a novel 7-O-modified geniste...
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Article
Adhesion behavior of endothelial progenitor cells to endothelial cells in simple shear flow
The adhesion of endothelial progenitor cells (EPCs) on endothelial cells (ECs) is one of the critical physiological processes for the regenesis of vascular vessels and the prevention of serious cardiovascular ...
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Article
RACK1 Regulates Src Activity on Apoptosis of Vascular Smooth Muscle Cells Induced by Cyclic Strain
Mechanical cyclic strain (CS) is an important regulator of apoptosis of vascular smooth muscle cells (VSMCs), which are involved in vascular remodeling during hypertension. However, its mechanism is still uncl...
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Article
Spontaneous Rhythmic Inward Currents Recorded in Interstitial Cells of Rabbit Portal Vein
It is now well established that smooth muscle of the portal vein exhibits spontaneous rhythmic contraction in vitro. The present study was designed to investigate the pacemaking mechanism(s) underlying the spo...
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Article
Normal Shear Stress and Vascular Smooth Muscle Cells Modulate Migration of Endothelial Cells Through Histone Deacetylase 6 Activation and Tubulin Acetylation
Endothelial cells (ECs) line the innermost of the blood vessel wall and are constantly subjected to shear stress imposed by blood flow. ECs were also influenced by the neighboring vascular smooth muscle cells ...
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Article
Design and application of dynamic monitoring and visualization management information system of karst land rocky desertification
In order to study the spatial-temporal change and environmental management of regional karst LUCC (land use and land cover change) and its causative environmental effect—rocky desertification by integrating qu...
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Article
Ecological security evaluation of sustainable agricultural development in karst mountainous area
Ecological security is the main task and applied field of present geography, resources and environment sciences and ecology.Ecological security evaluation will efficiently promote ecological security and envir...
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Article
Sustainable use of land resource and its evaluation in county area
Sustainable use of natural resources is different from sustainable development. As the most important natural resource, sustainable use of land resource is the essential guarantee of sustainable development. T...